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Clinical Investigation of the Inhibitory Effects of Tooth-Coating Materials on Initial Active Root Caries : A Pilot Randomized Controlled Trial

https://tokushima-u.repo.nii.ac.jp/records/2000181
https://tokushima-u.repo.nii.ac.jp/records/2000181
e69c9f66-853f-46c7-bab8-c48233f6b210
名前 / ファイル ライセンス アクション
medicina_60_1_150.pdf medicina_60_1_150.pdf (1.4 MB)
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アイテムタイプ 文献 / Documents(1)
公開日 2024-10-16
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
出版社版DOI
関連識別子 https://doi.org/10.3390/medicina60010150
関連名称 10.3390/medicina60010150
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
タイトル
タイトル Clinical Investigation of the Inhibitory Effects of Tooth-Coating Materials on Initial Active Root Caries : A Pilot Randomized Controlled Trial
著者 Asahi, Yoko

× Asahi, Yoko

en Asahi, Yoko

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Naito, Katsuaki

× Naito, Katsuaki

en Naito, Katsuaki

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Kanda, Hikaru

× Kanda, Hikaru

en Kanda, Hikaru

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Niwano, Kazuaki

× Niwano, Kazuaki

en Niwano, Kazuaki

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武川, 大輔

× 武川, 大輔

WEKO 566
徳島大学 教育研究者総覧 246736/profile-ja.html
e-Rad_Researcher 10632664

ja 武川, 大輔
武川, 大輔
ISNI

ja-Kana タケガワ, ダイスケ
タケガワ, ダイスケ

en Takegawa, Daisuke
Takegawa, Daisuke

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湯本, 浩通

× 湯本, 浩通

WEKO 1691
徳島大学 教育研究者総覧 60390/profile-ja.html
e-Rad_Researcher 60284303

ja 湯本, 浩通
湯本, 浩通
ISNI

ja-Kana ユモト, ヒロミチ
ユモト, ヒロミチ

en Yumoto, Hiromichi
Yumoto, Hiromichi

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Noiri, Yuichiro

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en Noiri, Yuichiro

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Hayashi, Mikako

× Hayashi, Mikako

en Hayashi, Mikako

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抄録
内容記述 Background and Objectives: Caredyne ZIF-C is a novel, capsule-mixed zinc-containing prototype glass ionomer cement (GIC). Zinc ions are reported to inhibit root dentin demineralization, dentin collagen degradation, bacterial growth, acid production, and in vitro bacterial biofilm formation. However, the effectiveness of GICs against initial root caries lesions is unclear. Therefore, this study aimed to evaluate the efficacy of GICs, especially the new zinc-containing Caredyne ZIF-C GIC, as tooth-coating materials in patients with initial active root caries. Materials and Methods: A total of 58 lesions in 47 older adults (age > 65 years) were randomly allocated to one of the following three groups: Caredyne ZIF-C, Fuji VII (a conventional GIC), and sodium fluoride (NaF). All the lesions were treated with the assigned materials without removing the infected dentin, and the rates of dental plaque attachment and coating material fall-out were evaluated after 3, 6, and 12 months. The failure rate was defined as the number of teeth that needed restoration due to caries progression. Results: The plaque attachment rates tended to be lower in the material-coated root surfaces than in the healthy exposed root surfaces after 3, 6, and 12 months, although the differences among the three groups were not significant. Moreover, the coating material fall-out rate tended to be lower in the Caredyne ZIF-C group than in the Fuji VII group. There was no significant difference in the failure rate among the three groups at the 12 months mark. Conclusions: Though this pilot study offers a new direction for suppressing the progression of initial active root caries by controlling plaque attachment using GICs including Caredyne ZIF-C, clinical studies with a larger sample size are needed.
キーワード
主題 root caries
キーワード
主題 secondary prevention
キーワード
主題 glass ionomer cement
キーワード
主題 Caredyne ZIF-C
キーワード
主題 biofilm
書誌情報 en : Medicina

巻 60, 号 1, p. 150, 発行日 2024-01-13
収録物ID
収録物識別子タイプ EISSN
収録物識別子 16489144
出版者
出版者 MDPI
権利情報
権利情報 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
EID
識別子 407921
言語
言語 eng
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