| Item type |
文献 / Documents(1) |
| 公開日 |
2024-10-22 |
| アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 出版社版DOI |
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関連識別子 |
https://doi.org/10.1038/s41380-023-02224-7 |
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関連名称 |
10.1038/s41380-023-02224-7 |
| 出版タイプ |
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|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
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タイトル |
Cerebral cortical structural alteration patterns across four major psychiatric disorders in 5549 individuals |
| 著者 |
Matsumoto, Junya
Fukunaga, Masaki
Miura, Kenichiro
Nemoto, Kiyotaka
Okada, Naohiro
Hashimoto, Naoki
Morita, Kentaro
Koshiyama, Daisuke
Ohi, Kazutaka
Takahashi, Tsutomu
Koeda, Michihiko
Yamamori, Hidenaga
Fujimoto, Michiko
Yasuda, Yuka
Ito, Satsuki
Yamazaki, Ryuichi
Hasegawa, Naomi
Narita, Hisashi
Yokoyama, Satoshi
Mishima, Ryo
Miyata, Jun
Kobayashi, Yuko
Sasabayashi, Daiki
Harada, Kenichiro
Yamamoto, Maeri
Hirano, Yoji
Itahashi, Takashi
中瀧, 理仁
Hashimoto, Ryu-ichiro
Tha, Khin K.
Koike, Shinsuke
Matsubara, Toshio
Okada, Go
Yoshimura, Reiji
Abe, Osamu
van Erp, Theo G. M.
Turner, Jessica A.
Jahanshad, Neda
Thompson, Paul M.
Onitsuka, Toshiaki
Watanabe, Yoshiyuki
Matsuo, Koji
Yamasue, Hidenori
Okamoto, Yasumasa
Suzuki, Michio
Ozaki, Norio
Kasai, Kiyoto
Hashimoto, Ryota
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| 抄録 |
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内容記述 |
According to the operational diagnostic criteria, psychiatric disorders such as schizophrenia (SZ), bipolar disorder (BD), major depressive disorder (MDD), and autism spectrum disorder (ASD) are classified based on symptoms. While its cluster of symptoms defines each of these psychiatric disorders, there is also an overlap in symptoms between the disorders. We hypothesized that there are also similarities and differences in cortical structural neuroimaging features among these psychiatric disorders. T1-weighted magnetic resonance imaging scans were performed for 5,549 subjects recruited from 14 sites. Effect sizes were determined using a linear regression model within each protocol, and these effect sizes were meta-analyzed. The similarity of the differences in cortical thickness and surface area of each disorder group was calculated using cosine similarity, which was calculated from the effect sizes of each cortical regions. The thinnest cortex was found in SZ, followed by BD and MDD. The cosine similarity values between disorders were 0.943 for SZ and BD, 0.959 for SZ and MDD, and 0.943 for BD and MDD, which indicated that a common pattern of cortical thickness alterations was found among SZ, BD, and MDD. Additionally, a generally smaller cortical surface area was found in SZ and MDD than in BD, and the effect was larger in SZ. The cosine similarity values between disorders were 0.945 for SZ and MDD, 0.867 for SZ and ASD, and 0.811 for MDD and ASD, which indicated a common pattern of cortical surface area alterations among SZ, MDD, and ASD. Patterns of alterations in cortical thickness and surface area were revealed in the four major psychiatric disorders. To our knowledge, this is the first report of a cross-disorder analysis conducted on four major psychiatric disorders. Cross-disorder brain imaging research can help to advance our understanding of the pathogenesis of psychiatric disorders and common symptoms. |
| 書誌情報 |
en : Molecular Psychiatry
巻 28,
号 11,
p. 4915-4923,
発行日 2023-08-18
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| 収録物ID |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
13594184 |
| 収録物ID |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
14765578 |
| 収録物ID |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12909982 |
| 収録物ID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11164978 |
| 出版者 |
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|
出版者 |
Springer Nature |
| 権利情報 |
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|
権利情報 |
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
| EID |
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|
識別子 |
406154 |
| 言語 |
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|
言語 |
eng |
mp_28_11_4915.pdf (2.4 MB)
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