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Crucial role of renin-angiotensin system in the pathogenesis of atherosclerosis
https://tokushima-u.repo.nii.ac.jp/records/2001161
https://tokushima-u.repo.nii.ac.jp/records/2001161c6d29e0f-7ffd-4162-8a8e-de660a58d95d
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
LID201112262002.pdf (844 KB)
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| Item type | 文献 / Documents(1) | |||||||||||
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| 公開日 | 2011-12-26 | |||||||||||
| アクセス権 | ||||||||||||
| アクセス権 | open access | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | journal article | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Crucial role of renin-angiotensin system in the pathogenesis of atherosclerosis | |||||||||||
| 著者 |
佐田, 政隆
× 佐田, 政隆
WEKO
309
× 福田, 大受 |
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| 抄録 | ||||||||||||
| 内容記述 | The renin-angiotensin system (RAS) has been demonstrated to play a critical role in the initiation and progression of atherosclerosis, thereby contributing to development of cardiovascular diseases. Angiotensin II (Ang II), a major substrate in RAS, stimulates atherosclerosis through various deleterious effects such as endothelial dysfunction, cellular proliferation and inflammation. Recently, local RAS in vasculature is reported to play an important role. Many of these atherogenic actions of Ang II are mediated by reactive oxygen species (ROS). Investigation of the role of ROS and inflammation induced by RAS may provide a clue to understanding the pathophysiology of atherosclerotic diseases, and may lead to a new therapeutic strategy. | |||||||||||
| キーワード | ||||||||||||
| 主題 | atherosclerosis | |||||||||||
| キーワード | ||||||||||||
| 主題 | renin-angiotensin system | |||||||||||
| キーワード | ||||||||||||
| 主題 | reactive oxygen species | |||||||||||
| キーワード | ||||||||||||
| 主題 | inflammation | |||||||||||
| 書誌情報 |
en : The journal of medical investigation : JMI 巻 57, 号 1-2, p. 12-25, 発行日 2010-02 |
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| 収録物ID | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 13431420 | |||||||||||
| 収録物ID | ||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||
| 収録物識別子 | AA11166929 | |||||||||||
| 備考 | ||||||||||||
| 値 | The journal of medical investigation : http://medical.med.tokushima-u.ac.jp/jmi/index.html | |||||||||||
| EID | ||||||||||||
| 識別子 | 207239 | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
