| Item type |
文献 / Documents(1) |
| 公開日 |
2011-12-14 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Diagnosis of the presence of lymph node metastasis and decision of operative indication using fluorodeoxyglucose-positron emission tomography and computed tomography in patients with primary lung cancer |
|
言語 |
en |
| 著者 |
鳥羽, 博明
近藤, 和也
大塚, 秀樹
滝沢, 宏光
監崎, 孝一郎
先山, 正二
丹黒, 章
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Objectives : We evaluate whether integrated fluorodeoxyglucose-positron emission tomography and computed tomography (FDG-PET/CT) scan can diagnose the presence of lymph node metastasis more accurately than computed tomography (CT) scan alone. Methods : Forty-two patients with lung cancer preoperatively underwent integrated PET/CT scan using FDG and CT scan and underwent pulmonary resection and lymph node dissection. We judged cases as lymph node metastasis if the lymph node visually accumulated FDG at PET/CT scan and measured 1 cm or greater in the short axis at CT scan. We retrospectively analyzed whether our judgments in each modality were consistent with the pathological diagnosis. Results : Two-hundred and seventeen stations of lymph node were dissected and 21 stations (9.7%) were histologically diagnosed as positive metastasis. Thirty-two stations of lymph node visually accumulated FDG at PET/CT scan and 17 stations measured 1 cm or greater in the short axis at CT scan. Concerning the diagnosis of lymph node metastasis, PET/CT scan showed significantly higher sensitivity than CT scan (81% vs. 48%, p=0.024). The false-positive rate was significantly high in PET-positive lymph nodes measuring less than 1 cm in diameter. There were 4 falsenegative lymph nodes with both scans. All of these were less than 7 mm in diameter and had a low percentage of metastatic foci in the lymph node. Concerning the diagnosis of N staging, there was no significant difference between PET/CT scan and CT scan (83% vs. 69%, p=0.124). However, the identification of N2 disease at PET/CT scan was significantly more accurate than that at CT scan (100% vs. 38%, p=0.031). Conclusions : PET/CT is superior to CT scan in lymph node staging. However, because the false-positive rate is high in PET-positive lymph nodes measuring less than 1 cm in diameter, we think that clinical background should be considered and other modalities or histological examinations should be undertaken if necessary. |
|
言語 |
en |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
fluorodeoxyglucose-positron emission tomography and computed tomography scan |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
computed tomography scan |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
lung cancer |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
lymph node metastasis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
diagnosis |
| 書誌情報 |
en : The journal of medical investigation : JMI
巻 57,
号 3-4,
p. 305-313,
発行日 2010-08
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13431420 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11166929 |
| 備考 |
|
|
言語 |
ja |
|
値 |
The journal of medical investigation : http://medical.med.tokushima-u.ac.jp/jmi/index.html |
| EID |
|
|
識別子 |
225951 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
LID201112142006.pdf (670 KB)
