細菌感染症患者におけるスタチンの多面的効果

Statins, treatments for dyslipidemia, have been reported to possess effects leading to the repair of the vascular endothelium, as well as anti-oxidative and anti-inflammatory effects, and their clinical usefulness has been focused on. It was also reported in previous clinical research that bacteremia patients on statins showed a lower mortality compared to those not receiving statins, and atherosclerosis patients on statins showed a significantly lower rate of severe or fatal sepsis compared to those not receiving them. We conducted a case-control study involving patients hospitalized in Tokushima University Hospital to evaluate the relationship between taking／not taking statins and bacterial infectious diseases. As a result, there was no relationship between taking／not taking statins and the overall patients with bacterial infectious diseases, but sepsis patients on statins showed a significantly lower mortality. The taking of statins was suggested to be useful for patients with bacterial infectious diseases, particularly males.

キーワード

主題

statin

キーワード

主題

multiple effect

キーワード

主題

bacterial infection

キーワード

主題

sepsis

書誌情報

ja : 四国医学雑誌

巻 68, 号 1-2, p. 29-34, 発行日 2012-04-25

収録物ID

収録物識別子タイプ

ISSN

収録物識別子

00373699

収録物ID

収録物識別子タイプ

NCID

収録物識別子

AN00102041

出版者

徳島医学会

備考

値

四国医学雑誌 : http://www.tokushima-u.ac.jp/med/research/shikoku_acta_medica.html

EID

識別子

247877

言語

jpn

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