Item type |
文献 / Documents(1) |
公開日 |
2014-03-05 |
アクセス権 |
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アクセス権 |
open access |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
タイトル |
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タイトル |
Visual and semi-quantitative assessment of brain tumors using 201Tl-SPECT |
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言語 |
en |
著者 |
ノセ, アユミ
大塚, 秀樹
ノセ, ハヤト
音見, 暢一
テラザワ, カオリ
原田, 雅史
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抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Objective : To evaluate the usefulness of 201Tl-SPECT in differentiating benign from malignant brain tumors. Methods and Materials : Eighty-eight patients (44 males and 44 females) with 58 high-grade (WHO grade III-IV) and 30 low-grade (WHO grade III) tumors were evaluated with 201Tl-SPECT. (1) Visual assessment was performed by board-certificated radiologists using 201Tl-SPECT. Tumors were classified in two groups (Tl-positive and Tl-negative) and scored using the five grade evaluation system. Receiver operating characteristic (ROC) analysis was performed in the Tl-positive group. (2) Semi-quantitative assessment involved measurement of early and delayed 201Tl uptake, and the retention index (RI) was applied as follows : RI=delayed uptake ratio/early uptake ratio. Three combinations of RI using mean and maximum values of the region of interest were calculated. Results : (1) Seventy-four Tl-positive and 14 Tl-negative tumors. The area under the ROC curve (AUC) estimated by three radiologists exceeded a value of 0.7. The value was greater when estimated by the more experienced radiologist. (2) In all RIs, the difference of RI between high-grade tumors and low-grade tumors was statistically significant. Conclusion : A visual and semi-quantitative assessment using 201Tl-SPECT was found to be useful for differentiating benign from malignant brain tumors. |
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言語 |
en |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
201Tl-SPECT |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
brain tumors |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
retention index |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
differential diagnosis |
書誌情報 |
en : The journal of medical investigation : JMI
巻 60,
号 1-2,
p. 121-126,
発行日 2013-02
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収録物ID |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
13431420 |
収録物ID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA11166929 |
EID |
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識別子 |
269659 |
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識別子タイプ |
URI |
言語 |
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言語 |
eng |