| Item type |
文献 / Documents(1) |
| 公開日 |
2014-03-17 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Delayed-onset severe heparin-induced thrombocytopenia after total arch replacement under cardiopulmonary bypass |
|
言語 |
en |
| 著者 |
ナカヤマ, タイスケ
木下, 肇
菅野, 幹雄
黒部, 裕嗣
神原, 保
藤本, 鋭貴
北市, 隆
フジタ, ヒロシ
ソガベ, ヒトシ
北川, 哲也
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
An extremely rare case with delayed-onset heparin-induced thrombocytopenia (HIT) is described. A 46-year-old man underwent arch replacement for aortic dissection under cardiopulmonary bypass and initial exposure of unfractionated heparin. In post operative 7 days, persistent atrial fibrillation was occurred, so a continuous infusion of heparin (10000 IU/day) and Vitamine K antagonist (Warfarin) taking was started for preventing thrombosis. By 32 days after the operation, his platelet count had fallen (3×103 /μL) and oral hematoma and ecchymoma of bilateral lower legs were occurred. The value of HIT antibodies and the IgG antibody was 2.485 and 1.586 on 32-postoperative day, respectively. Heparin was immediately discontinued, and argatroban administrated. Platelet exceeded above 100×103/μL on 12 days of the therapy. To our knowledge, few cases of delayed-onset severe HIT associated with CPB surgery have been reported in Japan. |
|
言語 |
en |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
heparin-induced thrombocytopenia |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
aortic surgery |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
unfractionated heparin |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
heparin-platelet factor 4 complex |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
argatroban |
| 書誌情報 |
en : The journal of medical investigation : JMI
巻 60,
号 1-2,
p. 154-158,
発行日 2013-02
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13431420 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11166929 |
| EID |
|
|
識別子 |
266135 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
LID201403172002.pdf (374 KB)
