| Item type |
文献 / Documents(1) |
| 公開日 |
2015-07-30 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.2152/jmi.60.213 |
|
|
言語 |
ja |
|
|
関連名称 |
10.2152/jmi.60.213 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Quantitative analysis of hemodynamics of congested island flaps under leech therapy |
|
言語 |
en |
| 著者 |
柏木, 圭介
橋本, 一郎
安倍, 吉郎
コウツ, クニオ
ヤマノ, マサヒロ
中西, 秀樹
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Background A congested flap is a good indication for leech therapy. However, determining the appropriate number of leeches as well as the appropriate application time in clinical cases is difficult. We analyzed hemodynamics in rabbit island flaps under leech therapy to find a suitable clinical procedure for determining the appropriate number of leeches to be used and the duration of therapy. Methods Island flaps were raised in 35 rabbit ears, and congestion was induced by venous clamping. Treatment involved use of 1 or 3 leeches and was begun 60 minutes after venous occlusion. Flaps were examined for area of surviving tissue, alterations in transcutaneous oxygen and carbon dioxide tension (TcPO2 and TcPCO2), and flow volume. Arteriole and venule diameters and flow velocities were examined microscopically. Results Flap survival area in the 3-leech therapy group was significantly larger than the 1-leech therapy group and the control group. With 3- leech therapy, TcPCO2 decreased significantly, as did arteriole and venule diameters. After clamp release, TcPCO2 and venule diameter continued to decrease in this group, and flow velocity increased significantly. Conclusions Leech therapy may salvage compromised flaps by replacing congested blood with new arterial blood and thus maintaining flap viability. TcPO2 and TcPCO2 monitoring may help evaluate the therapeutic effect and determine the appropriate number of leeches to apply and the duration of therapy. |
|
言語 |
en |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
leech therapy |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
congestion |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
island flap |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
microcirculation |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
TcPO2 and TcPCO2 monitoring |
| 書誌情報 |
en : The journal of medical investigation : JMI
巻 60,
号 3-4,
p. 213-220,
発行日 2013-08
|
| 収録物ID |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13431420 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11166929 |
| EID |
|
|
識別子 |
283569 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
LID201507305001.pdf (1.22 MB)
