WEKO3
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RootNode
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Effects of Decreased Occlusal Loading during Growth on the Mandibular Bone Characteristics
https://tokushima-u.repo.nii.ac.jp/records/2002938
https://tokushima-u.repo.nii.ac.jp/records/2002938b89e7996-b4a2-4650-a240-7441ea19bb0e
| 名前 / ファイル | ライセンス | アクション |
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LID201606141001.pdf (142 KB)
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LID201606141002.pdf (407 KB)
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LID201606141003.pdf (3.15 MB)
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| Item type | 文献 / Documents(1) | |||||||||||||||
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| 公開日 | 2016-06-15 | |||||||||||||||
| アクセス権 | ||||||||||||||||
| アクセス権 | open access | |||||||||||||||
| 資源タイプ | ||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||||||||
| 資源タイプ | doctoral thesis | |||||||||||||||
| 出版社版DOI | ||||||||||||||||
| 関連識別子 | https://doi.org/10.1371/journal.pone.0129290 | |||||||||||||||
| 関連名称 | 10.1371/journal.pone.0129290 | |||||||||||||||
| 出版タイプ | ||||||||||||||||
| 出版タイプ | NA | |||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_be7fb7dd8ff6fe43 | |||||||||||||||
| タイトル | ||||||||||||||||
| タイトル | Effects of Decreased Occlusal Loading during Growth on the Mandibular Bone Characteristics | |||||||||||||||
| タイトル別表記 | ||||||||||||||||
| その他のタイトル | 成長期における咀嚼性刺激の減少が下顎骨の性状に及ぼす影響 | |||||||||||||||
| タイトル別表記 | ||||||||||||||||
| その他のタイトル | Effects of Decreased Loading on the Mandible | |||||||||||||||
| 著者 |
七條, なつ子
× 七條, なつ子× 田中, 栄二
WEKO
323
× 川合, 暢彦× Ruijven, Leo J. van
× Langenbach, Geerling E. J.
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| 抄録 | ||||||||||||||||
| 内容記述 | Background Bone mass and mineralization are largely influenced by loading. The purpose of this study was to evaluate the reaction of the entire mandibular bone in response to decreased load during growth. It is hypothesized that decreased muscular loading will lead to bone changes as seen during disuse, i.e. loss of bone mass. Methods and Findings Ten 21-day-old Wistar strain male rats were divided into two groups (each n=5) and fed on either a hard- or soft-diet for 11 weeks. Micro-computed tomography was used for the investigation of bone mineralization, bone volume, bone volume fraction (BV/TV) and morphological analysis. Mandibular mineralization patterns were very consistent, showing a lower degree of mineralization in the ramus than in the corpus. In the soft-diet group, mineralization below the molars was significantly increased (p<0.05) compared to the hard diet group. Also, bone volume and BV/TV of the condyle and the masseter attachment were decreased in the soft-diet group (p<0.05). Morphological analysis showed inhibited growth of the ramus in the soft-diet group (p<0.05). Conclusion Decreased loading by a soft diet causes significant changes in the mandible. However, these changes are very region-specific, probably depending on the alterations in the local loading regime. The results suggest that muscle activity during growth is very important for bone quality and morphology. |
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| キーワード | ||||||||||||||||
| 主題 | muscle activity | |||||||||||||||
| キーワード | ||||||||||||||||
| 主題 | loading stimulus | |||||||||||||||
| キーワード | ||||||||||||||||
| 主題 | bone remodeling | |||||||||||||||
| キーワード | ||||||||||||||||
| 主題 | mineralization | |||||||||||||||
| 書誌情報 |
en : PLOS ONE 巻 10, 号 6, p. e0129290, 発行日 2015-06-10 |
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| 収録物ID | ||||||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||||||
| 収録物識別子 | 19326203 | |||||||||||||||
| 出版者 | ||||||||||||||||
| 出版者 | PLOS | |||||||||||||||
| 備考 | ||||||||||||||||
| 値 | 内容要旨・審査要旨・論文本文の公開: 内容要旨 : LID201606141001.pdf 審査要旨 : LID201606141002.pdf 論文本文 : LID201606141003.pdf 本論文は, 著者Natsuko Hichijoの学位論文として提出され, 学位審査・授与の対象となっている。 学位授与者所属 : 徳島大学大学院口腔科学教育部（口腔科学専攻） |
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| 権利情報 | ||||||||||||||||
| 権利情報 | Copyright: © 2015 Hichijo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | |||||||||||||||
| EID | ||||||||||||||||
| 識別子 | 295273 | |||||||||||||||
| 言語 | ||||||||||||||||
| 言語 | eng | |||||||||||||||
| 報告番号 | ||||||||||||||||
| 学位授与番号 | 甲第2939号 | |||||||||||||||
| 学位記番号 | ||||||||||||||||
| 値 | 甲口第404号 | |||||||||||||||
| 学位授与年月日 | ||||||||||||||||
| 学位授与年月日 | 2016-03-23 | |||||||||||||||
| 学位名 | ||||||||||||||||
| 学位名 | 博士（歯学） | |||||||||||||||
| 学位授与機関 | ||||||||||||||||
| 学位授与機関名 | 徳島大学 | |||||||||||||||
