WEKO3
アイテム
唾液腺の構造と機能
https://tokushima-u.repo.nii.ac.jp/records/2003102
https://tokushima-u.repo.nii.ac.jp/records/2003102e5096ba5-4ca7-48ac-8c12-8a1199e5e85d
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
LID201608054007.pdf (3.65 MB)
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| Item type | 文献 / Documents(1) | |||||||||||
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| 公開日 | 2016-08-05 | |||||||||||
| アクセス権 | ||||||||||||
| アクセス権 | open access | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | journal article | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| タイトル | ||||||||||||
| タイトル | 唾液腺の構造と機能 | |||||||||||
| タイトル | ||||||||||||
| タイトル | ダエキセン ノ コウゾウ ト キノウ | |||||||||||
| タイトル別表記 | ||||||||||||
| その他のタイトル | Structure and Function of the Salivary Gland | |||||||||||
| 著者 |
赤松, 徹也
× 赤松, 徹也
WEKO
1686
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| 抄録 | ||||||||||||
| 内容記述 | The salivary gland is developed under the epithelial-mesenchymal interaction and formed by repeating branching morphogenesis, which is a common process in the development of the glandular tissues. Although the differentiation and maturation of salivary gland is continued into early postnatal life, the fundamental ability of saliva secretion is already expressed after birth. These development, differentiation, and maturation of salivary gland are regulated by many growth/ differentiation factors, which are initially synthesized as inactive precursors and activated by the limited proteolysis. On the other hand, saliva secretion is one of the important physiological functions of the salivary gland and occurs dependently on the increase of the osmolality in the lumen through two pathways, paracellular and transcellular pathways. It is revealed that a water channel aquaporin 5 (AQP5) is involved in saliva secretion through the latter pathway. Saliva contains various components, which express various physiological functions of saliva. Because the oral cavity is confronted with hazards of various allergens from the outside continuously, the salivary gland produces and secretes various factors as the defense system. Saliva is, therefore, one of an important body fluid to maintain the oral health, and the decrease of saliva secretion causes xerostomia/dry mouth, which affects not only oral disease and dysfunction but also systemic disease. We previously reported the involvement of a subtilisin-like proprotein convertase PACE4 in the development and differentiation of salivary gland, lipopolysaccharide-mediated induction of inflammatory cytokines in the salivary gland, degradation of salivary AQP5 by parasympathetic denervation, and so on. This review will describe the structure and function of the salivary gland, from its development to functional expression and regulation. |
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| キーワード | ||||||||||||
| 主題 | 唾液腺 | |||||||||||
| キーワード | ||||||||||||
| 主題 | 唾液 | |||||||||||
| キーワード | ||||||||||||
| 主題 | 水チャネル | |||||||||||
| キーワード | ||||||||||||
| 主題 | サチライシン様前駆体蛋白質変換酵素 | |||||||||||
| 書誌情報 |
en : Journal of Oral Health and Biosciences 巻 28, 号 2, p. 77-86, 発行日 2016-02-29 |
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| 収録物ID | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 21887888 | |||||||||||
| 収録物ID | ||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||
| 収録物識別子 | AA12713630 | |||||||||||
| 出版者 | ||||||||||||
| 出版者 | 四国歯学会 | |||||||||||
| EID | ||||||||||||
| 識別子 | 329725 | |||||||||||
| 言語 | ||||||||||||
| 言語 | jpn | |||||||||||
