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歯根象牙質形成を再考する
https://tokushima-u.repo.nii.ac.jp/records/2003104
https://tokushima-u.repo.nii.ac.jp/records/2003104e4abf6cf-8801-4677-8275-23947b6eedc4
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
LID201608054009.pdf (1.82 MB)
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| Item type | 文献 / Documents(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-08-05 | |||||
| アクセス権 | ||||||
| アクセス権 | open access | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| タイトル | ||||||
| タイトル | 歯根象牙質形成を再考する | |||||
| 言語 | ja | |||||
| タイトル | ||||||
| タイトル | シコン ゾウゲシツ ケイセイ オ サイコウ スル | |||||
| 言語 | ja-Kana | |||||
| タイトル別表記 | ||||||
| その他のタイトル | The New Insight into Radicular Dentin Formation | |||||
| 言語 | en | |||||
| 著者 |
馬場, 麻人
× 馬場, 麻人 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Dentin is mineralized connective tissue, which consists of two parts, coronal dentin covered by enamel and radicular dentin by cementum. Although both parts are formed by odontoblasts, biophysical and biochemical properties are indeed different, which evoke the specific system for radicular dentin formation. One of the critical factor of radicular dentin formation is Hertwig's epithelial root sheath (HERS), which leads proliferation and differentiation of odontoblasts under the control of TGF-β/BMP signaling, and the ablation or over-expression of constituent molecules showed the specific malformation of radicular dentin. Wnt/β-catenin signaling is the other candidate of dentin formation which may regulate differently on crown and root formation. Fibroblast growth factor (FGF) 18 is possible downstream molecule of this signaling. Interestingly, the expression of FGF18 transcripts was detected during root formation, but not crown formation in rat mandibular molar. While possible receptors, FGFR2 and FGFR3, were continuously observed in both crown and root formation, those suggested that coronal and radicular dentin might be formed under the continuous and/or reciprocal control of different FGFs. The clarification of these systems may open new insight into the tissue regeneration and/or engineering of tooth and periodontium. |
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| 言語 | en | |||||
| キーワード | ||||||
| 言語 | ja | |||||
| 主題Scheme | Other | |||||
| 主題 | 歯根象牙質 | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Hertwig's epithelial root sheath (HERS) | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Wnt/β-Catenin | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | fibroblast growth factor (FGF) | |||||
| 書誌情報 |
en : Journal of Oral Health and Biosciences 巻 29, 号 1, p. 1-6, 発行日 2016-06-30 |
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| 収録物ID | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 21887888 | |||||
| 収録物ID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA12713630 | |||||
| 出版者 | ||||||
| 出版者 | 四国歯学会 | |||||
| 言語 | ja | |||||
| EID | ||||||
| 識別子 | 327259 | |||||
| 識別子タイプ | URI | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
