| Item type |
文献 / Documents(1) |
| 公開日 |
2017-04-21 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
関連識別子 |
https://doi.org/10.2131/fts.3.121 |
|
|
関連名称 |
10.2131/fts.3.121 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Methyl cinnamate increases cell vulnerability to oxidative stress induced by hydrogen peroxide in rat thymocytes |
| 著者 |
ツズキ, ヒロミツ
イノウエ, ショウタ
コバヤシ, ダイキ
Uuganbaatar, Gantulga
金丸, 芳
横井川, 久己男
小山, 保夫
|
| 抄録 |
|
|
内容記述 |
Methyl cinnamate (MC) and essential oils containing MC possess beneficial antimicrobial, antifungal, and insecticidal effects, among ohters. Such effects are related to the biocidal action of MC. The antioxidant activity of MC has also been reported elsewhere. It has been suggested that MC may be cytotoxic to cells exposed to oxidative stress. To test this possibility, the effect of MC on rat thymocytes was examined while the cells were subjected to oxidative stress induced by hydrogen peroxide (H2O2). Flow cytometric techniques with appropriate fluorescent probes were used for quantification. MC increased cell vulnerability to oxidative stress via acceleration of the cell death process and/or poteniation of oxidative stress. The use of MC is widespread because of its beneficial actions, and thus further attention should be paid to whether MC is effective under oxidative stress. |
| キーワード |
|
|
主題 |
Methyl cinnamate |
| キーワード |
|
|
主題 |
Hydrogen peroxide |
| キーワード |
|
|
主題 |
Cytotoxicity |
| キーワード |
|
|
主題 |
Lymphocytes |
| キーワード |
|
|
主題 |
Oxidative stress |
| 書誌情報 |
en : Fundamental Toxicological Sciences
巻 3,
号 3,
p. 121-125,
発行日 2016
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
2189115X |
| 権利情報 |
|
|
権利情報 |
Copyright © 2016 The Japanese Society of Toxicology |
| EID |
|
|
識別子 |
311924 |
| 言語 |
|
|
言語 |
eng |
LID201704212001.pdf (1.12 MB)
