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Evaluation of episodes of sleep apnea in patients with liver cirrhosis
https://tokushima-u.repo.nii.ac.jp/records/2003999
https://tokushima-u.repo.nii.ac.jp/records/2003999088c38e7-db6a-4f8d-89d8-f0550f4b35ac
| 名前 / ファイル | ライセンス | アクション |
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jmi_53_1-2_159.pdf (213 KB)
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| Item type | 文献 / Documents(1) | |||||||||||||||||||||||
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| 公開日 | 2017-12-07 | |||||||||||||||||||||||
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| アクセス権 | open access | |||||||||||||||||||||||
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| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||||||
| 出版社版DOI | ||||||||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||||||||
| 関連識別子 | https://doi.org/10.2152/jmi.53.159 | |||||||||||||||||||||||
| 言語 | ja | |||||||||||||||||||||||
| 関連名称 | 10.2152/jmi.53.159 | |||||||||||||||||||||||
| 出版タイプ | ||||||||||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||||||
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| タイトル | Evaluation of episodes of sleep apnea in patients with liver cirrhosis | |||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||
| 著者 |
オガタ, タツロウ
× オガタ, タツロウ
× 野村, 昌弘
× 中屋, 豊
WEKO
1577
× 伊東, 進 |
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| 抄録 | ||||||||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||||||||
| 内容記述 | Objective : Obstructive sleep apnea syndrome (OSAS) has been reported to be a new complication of liver cirrhosis with ascites. This fact prompted a study of episodes of sleep apnea as a function of the severity of cirrhosis. Methods : Forty eight patients with type Cliver cirrhosis were divided according to the Child- Pugh score into 3 groups : Group A (16 patients with grade A cirrhosis), Group B (16 patients with grade B cirrhosis), and Group C (16 patients with grade C cirrhosis). Portable sleep polygraphs (Fuji RC, Inc. Tokyo, Japan) were attached to the subjects, and oronasal respiration, tracheal sounds, respiratory movements of the chest, and percutaneous arterial oxygen saturation continuously were recorded. A decrease in the mean airflow to 50% or less was defined as hypopnea, and the number per hour of episodes of apnea and hypopnea per hour lasting 10 seconds or longer (AHI) was counted. A Holter ECG was also recorded, and spectral heart rate variability during sleep was analyzed by measuring low frequency power (0.04-0.15 Hz, LF power), high frequency power (0.15-0.40 Hz, HF power), the ratio of LF power to HF power (LF/HF ratio), and very low frequency power (0.008-0.04 Hz, VLF power). The difference in QT interval between the lead CM5 and the lead CM1 (QTc dispersion) was also examined. Results : AHI was significantly higher in Group C than in Groups A and B (p<0.05). In Group C, 6 patients with 20 times or more AHI per hour, obstructive sleep apnea, in which respiratory chest movements occur but oronasal respiration decreases or disappears, was observed. Spectral analyses of heart rate variability showed a decrease in HF power without sleep apnea, but increases in HF power and VLF power were observed during sleep apnea. The QTc dispersion increased during episodes of sleep apnea. Conclusions : As the stage of liver cirrhosis advanced, sleep apnea appeared, and changes in autonomic nervous activities were observed. Furthermore, QTc dispersion was increased during episodes of sleep apnea, presumably increasing the risk of ventricular arrhythmia. | |||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||
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| 言語 | en | |||||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||||
| 主題 | liver cirrhosis | |||||||||||||||||||||||
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| 言語 | en | |||||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||||
| 主題 | autonomic nervous | |||||||||||||||||||||||
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| 言語 | en | |||||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||||
| 主題 | QT dispersion | |||||||||||||||||||||||
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| 言語 | en | |||||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||||
| 主題 | sleep apnea | |||||||||||||||||||||||
| 書誌情報 |
en : The journal of medical investigation : JMI 巻 53, 号 1-2, p. 159-166, 発行日 2006-02 |
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| 収録物識別子タイプ | ISSN | |||||||||||||||||||||||
| 収録物識別子 | 13431420 | |||||||||||||||||||||||
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| 収録物識別子タイプ | NCID | |||||||||||||||||||||||
| 収録物識別子 | AA11166929 | |||||||||||||||||||||||
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| 識別子 | 136633 | |||||||||||||||||||||||
| 識別子タイプ | URI | |||||||||||||||||||||||
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| 言語 | eng | |||||||||||||||||||||||
