| Item type |
文献 / Documents(1) |
| 公開日 |
2018-03-02 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.2152/jmi.64.20 |
|
|
言語 |
ja |
|
|
関連名称 |
10.2152/jmi.64.20 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Extracts of citrus Sudachi peel attenuate body weight gain in C57BL/6 mice fed a high-fat diet |
|
言語 |
en |
| 著者 |
コバヤシ, ヒトミ
ミタニ, マミ
ミナトガワ, ユカ
ハヤシ, サトコ
中本, 真理子
首藤, 恵泉
ニイ, ヨシタカ
酒井, 徹
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Citrus Sudachi is the special local product of Tokushima Prefecture, and over 98% of Sudachi consumed in Japan every year is produced in Tokushima Prefecture. In this study, we evaluated the function of sudachi peel extract (SPE) using an animal model of obesity. C57BL/6 mice were fed a high-fat diet containing 1% SPE powder. Treatment with SPE significantly decreased body weight compared to that of mice fed a high-fat diet. A significant difference in body weight was observed between the control and SPE groups from 7 weeks after the start of the experiment, the significant difference continued until the end of the 14-week experiment. Reduction of blood glucose levels following insulin administration in SPE-treated mice was grater than that in control mice. Determination of mRNA expression in adipose tissue showed that the expression level of TNF-α in the SPE group was significantly decreased compared to that on the control group. These results suggest that SPE potentially has the ability to attenuate body weight gain. |
|
言語 |
en |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Citrus sudachi |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
high-fat diet |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
inflammation |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
weight |
| 書誌情報 |
en : The Journal of Medical Investigation
巻 64,
号 1-2,
p. 20-23,
発行日 2017-02
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13496867 |
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13431420 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11166929 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12022913 |
| 出版者 |
|
|
出版者 |
Faculty of Medicine Tokushima University |
|
言語 |
en |
| EID |
|
|
識別子 |
343663 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
jmi_64_1-2_20.pdf (387 KB)
