Item type |
文献 / Documents(1) |
公開日 |
2018-02-16 |
アクセス権 |
|
|
アクセス権 |
open access |
資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
出版社版DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.1016/j.bbamem.2017.03.020 |
|
|
言語 |
ja |
|
|
関連名称 |
10.1016/j.bbamem.2017.03.020 |
出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
タイトル |
|
|
タイトル |
Thermotropic and barotropic phase transitions on diacylphosphatidylethanolamine bilayer membranes |
|
言語 |
en |
著者 |
松木, 均
エンドウ, シゲル
スエヨシ, リョウスケ
後藤, 優樹
玉井, 伸岳
金品, 昌志
|
抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
The bilayer phase transitions of four diacylphosphatidylethanolamines (PEs) with matched saturated acyl chains (Cn = 12, 14, 16 and 18) and two PEs with matched unsaturated acyl chains containing a different kind of double bonds were observed by differential scanning calorimetry under atmospheric pressure and light-transmittance measurements under high pressure. The temperature-pressure phase diagrams for these PE bilayer membranes were constructed from the obtained phase-transition data. The saturated PE bilayer membranes underwent two different phase transitions related to the liquid crystalline (Lα) phase, the transition from the hydrated crystalline (Lc) phase and the chain melting (gel (Lβ) to Lα) transition, depending on the thermal history. Pressure altered the gel-phase stability of the bilayer membranes of PEs with longer chains at a low pressure. Comparing the thermodynamic quantities of the saturated PE bilayer membranes with those of diacylphosphatidylcholine (PC) bilayer membranes, the PE bilayer membranes showed higher phase-transition temperatures and formed more stable Lc phase, which originates from the strong interaction between polar head groups of PE molecules. On the other hand, the unsaturated PE bilayer membranes underwent the transition from the Lα phase to the inverted hexagonal (HII) phase at a high temperature and this transition showed a small transition enthalpy but high-pressure responsivity. It turned out that the kind of double bonds markedly affects both bilayer-bilayer and bilayer-nonbilayer transitions and the Lα/HII transition is a volume driven transition for the reconstruction of molecular packing. Further, the phase-transition behavior was explained by chemical potential curves of bilayer phases. |
|
言語 |
en |
キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Differential scanning calorimetry |
キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Lipid bilayer membrane |
キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Phase stability |
キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Phase transition |
キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Phosphatidylethanolamine |
キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Pressure |
書誌情報 |
en : Biochimica et Biophysica Acta (BBA) - Biomembranes
巻 1859,
号 7,
p. 1222-1232,
発行日 2017-03-31
|
収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
00052736 |
収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00564657 |
収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11522874 |
出版者 |
|
|
出版者 |
Elsevier |
|
言語 |
en |
権利情報 |
|
|
言語 |
en |
|
権利情報 |
© 2017 Elsevier B.V. All rights reserved. This manuscript version is made available under the CC-BY-NC-ND 4.0 license |
EID |
|
|
識別子 |
323559 |
|
識別子タイプ |
URI |
言語 |
|
|
言語 |
eng |