| Item type |
文献 / Documents(1) |
| 公開日 |
2018-04-23 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.2152/jmi.63.286 |
|
|
言語 |
ja |
|
|
関連名称 |
10.2152/jmi.63.286 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Analysis of the Prognostic Factors of Extensive Disease Small-Cell Lung Cancer Patients in Tokushima University Hospital |
|
言語 |
en |
| 著者 |
荻野, 広和
埴淵, 昌毅
柿内, 聡司
西條, 敦郎
手塚, 敏史
豊田, 優子
飛梅, 亮
大塚, 憲司
坂口, 暁
後東, 久嗣
有澤, 孝吉
西岡, 安彦
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Background : Small-cell lung cancer (SCLC) presents aggressive clinical behavior, and its prognosis is still poor. Previously, performance status (PS), or the existence of brain, bone, or liver metastasis were reported to be unfavorable prognostic factors. Given the recent progress of treatment modalities such as radiotherapy techniques and bone modifying agents, the prognostic factors might be different from previous findings. Therefore, we analyzed the prognostic factors of extensive disease SCLC (ED-SCLC) in recent years. Methods : ED-SCLC patients treated in Tokushima University Hospital between 2010 and 2016 were analyzed. Log-rank test and the Cox proportional hazards regression model was used in univariate and multivariate analysis, respectively. Results : Totally, 79 patients were analyzed. In the univariate analysis, age, PS, interstitial pneumonia (IP), liver metastasis, pleural dissemination, neutrophil counts, hypoalbuminemia, hypercalcemia and several liver and biliary enzymes were identified as poor prognostic factors. In the multivariate analysis, age, PS, IP, and liver and biliary enzymes were identified. Moreover, the PS in patients with liver metastasis was significantly worsened. Conclusions : In this study, we newly demonstrated that IP was a significant poor prognostic factor of ED-SCLC. Although liver metastasis was not extracted in multivariate analysis, it may have an impact on the prognosis of ED-SCLC. |
|
言語 |
en |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
extensive disease small-cell lung cancer (ED-SCLC) |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
prognostic factor |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
liver metastasis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
interstitial pneumonia |
| 書誌情報 |
en : The Journal of Medical Investigation
巻 63,
号 3-4,
p. 286-293,
発行日 2016-08
|
| 収録物ID |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13496867 |
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13431420 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11166929 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12022913 |
| 出版者 |
|
|
出版者 |
Faculty of Medicine Tokushima University |
|
言語 |
en |
| EID |
|
|
識別子 |
320101 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
jmi_63_3-4_286.pdf (286 KB)
