| Item type |
文献 / Documents(1) |
| 公開日 |
2018-05-10 |
| アクセス権 |
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|
アクセス権 |
open access |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
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|
関連識別子 |
https://doi.org/10.2152/jmi.62.37 |
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|
関連名称 |
10.2152/jmi.62.37 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Clinical role of Foxp3+regulatory T cell in Living donor related liver transplantation for prediction of life-threatening complications |
| 著者 |
アサノマ, ミチヒト
森, 大樹
池本, 哲也
宇都宮, 徹
居村, 暁
森根, 裕二
花岡, 潤
金本, 真美
齋藤, 裕
山田, 眞一郎
島田, 光生
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| 抄録 |
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内容記述 |
Purposes : It is no doubt that regulatory T cells (Foxp3+CD4+CD25+T cells : Treg) play important roles in transplant immunity.We investigated the significance of Treg expression in acute stage of living donorrelated liver transplantation (LDLT) for the possibility of the sensitive marker for immunological state and homeostatic stress after liver transplantation. Methods : Peripheral blood was drawn from 5 recipients of LDLT preoperatively and on post operative 1, 4, 7, and 14 days. The peripheral blood mononuclear cells (PBMCs) were stained with CD4, CD25, Foxp3, and were analyzed with FACScan. This data was compared with clinical output of LDLT. Result : The populations of Treg were significantly decreased in all patients on day 1 after LDLT and significantly increased in patients who had early postoperative complications compared with patients who had no complications. Conclusions : The population of Treg in peripheral blood may reflect the surgical stress such as life-threatening complications after LDLT. |
| キーワード |
|
|
主題 |
Liver transplantation |
| キーワード |
|
|
主題 |
regulatory T cells |
| キーワード |
|
|
主題 |
Foxp3 |
| キーワード |
|
|
主題 |
Transplant immunology |
| 書誌情報 |
en : The Journal of Medical Investigation
巻 62,
号 1-2,
p. 37-40,
発行日 2015-02
|
| 収録物ID |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13496867 |
| 収録物ID |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13431420 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11166929 |
| 収録物ID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12022913 |
| 出版者 |
|
|
出版者 |
Faculty of Medicine Tokushima University |
| EID |
|
|
識別子 |
306956 |
| 言語 |
|
|
言語 |
eng |
jmi_62_1-2_37.pdf (430 KB)
