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糖尿病における微量栄養素「鉄」の役割
https://tokushima-u.repo.nii.ac.jp/records/2004750
https://tokushima-u.repo.nii.ac.jp/records/200475066462132-6fd1-4501-a6cc-354bd949c398
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
sam_74_1-2_13.pdf (955 KB)
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| Item type | 文献 / Documents(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-05-14 | |||||
| アクセス権 | ||||||
| アクセス権 | open access | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| タイトル | ||||||
| タイトル | 糖尿病における微量栄養素「鉄」の役割 | |||||
| 言語 | ja | |||||
| タイトル別表記 | ||||||
| その他のタイトル | The role of iron, a trace nutrient, on diabetes | |||||
| 言語 | en | |||||
| 著者 |
池田, 康将
× 池田, 康将 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The nutrient balance is an important factor to keep healthy state in the body. In various nutrients, iron is a most abundant trace metal element. Iron-deficient anemia is often seen in the iron-related disorders, therefore, lots of functional food, drink, and nutritional supplement are widely provided and used to prevent iron deficiency. On the other hand, over iron intake induces excess iron status, causing increased oxidative stress production via catalyzing Fenton reaction. Recent evidences suggest that iron involves the pathological conditions of non-iron accumulating diseases, and the role of iron is noticed again. Diabetes is associated with poor prognosis to develop a variety of complications such as cardiovascular disease and diabetic kidney disease（DKD）in addition to diabetic retinopathy and neuropathy. Moreover, patients with diabetes often present reduced skeletal muscle mass, and it causes more impaired insulin resistance by diminishing glucose uptake. Recent studies have shown that iron content is associated with diabetic and obese condition, and high iron intake increases diabetes risk. We have clarified the favorable effect of iron reduction on obesity and DKD through diminishing oxidative stress. In addition, excess iron caused skeletal muscle atrophy and it was ameliorated by an anti-oxidant drug. Thus, iron plays an important role in diabetes and its complication through oxidative stress production. Further studies are clarifying an important role of trace nutrient including iron and so on, contributing to the development of new therapeutic strategy. |
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| 言語 | en | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Iron | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Diabetes | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Oxidative stress | |||||
| 書誌情報 |
ja : 四国医学雑誌 en : Shikoku Acta Medica 巻 74, 号 1-2, p. 13-20, 発行日 2018-04-25 |
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| 収録物ID | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00373699 | |||||
| 収録物ID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00102041 | |||||
| 出版者 | ||||||
| 出版者 | 徳島医学会 | |||||
| 言語 | ja | |||||
| EID | ||||||
| 識別子 | 347857 | |||||
| 識別子タイプ | URI | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
