| Item type |
文献 / Documents(1) |
| 公開日 |
2019-02-19 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
関連識別子 |
https://doi.org/10.1016/j.jff.2017.01.042 |
|
|
関連名称 |
10.1016/j.jff.2017.01.042 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Daily intake of Lactobacillus gasseri CP2305 improves mental, physical, and sleep quality among Japanese medical students enrolled in a cadaver dissection course |
| 著者 |
サワダ, ダイスケ
河合, 智子
西田, 憲生
桑野, 由紀
フジワラ, シゲル
六反, 一仁
|
| 抄録 |
|
|
内容記述 |
Increasing recognition of the interaction between the brain and gut microbiota has spurred interest in the efficacy of probiotics on stress-related behaviours. This study aimed to elucidate the effects of Lactobacillus gasseri CP2305 (CP2305) on mental and physical states in healthy male students enrolled in a cadaver dissection course in a double-blinded, placebo-controlled, crossover-designed trial. Daily administration of CP2305 for 4 weeks significantly improved anxiety, depressive mood and global sleep quality compared with placebo. CP2305 also suppressed salivary cortisol release. In the faecal microbiota, CP2305 suppressed the growth of Enterobacteriaceae. Differential changes in gene expression in peripheral blood leukocytes during the administration period were observed between the placebo and CP2305 groups. Eukaryotic initiation factor 2-related genes were down-regulated only in the placebo group. Thus, the ingestion of CP2305 may have beneficial effects on stress-associated behaviours. |
| キーワード |
|
|
主題 |
Probiotics |
| キーワード |
|
|
主題 |
Lactobacillus gasseri CP2305 |
| キーワード |
|
|
主題 |
Mental stress |
| キーワード |
|
|
主題 |
Insomnia |
| キーワード |
|
|
主題 |
Salivary cortisol |
| キーワード |
|
|
主題 |
Eukaryotic initiation factor 2 |
| 書誌情報 |
en : Journal of Functional Foods
巻 31,
p. 188-197,
発行日 2017-02-07
|
| 収録物ID |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
17564646 |
| 出版者 |
|
|
出版者 |
Elsevier |
| 権利情報 |
|
|
権利情報 |
©2017 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| EID |
|
|
識別子 |
344581 |
| 言語 |
|
|
言語 |
eng |
jff_31_188.pdf (761 KB)
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