| Item type |
文献 / Documents(1) |
| 公開日 |
2019-02-19 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.1016/j.jff.2017.06.031 |
|
|
言語 |
ja |
|
|
関連名称 |
10.1016/j.jff.2017.06.031 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Daily administration of paraprobiotic Lactobacillus gasseri CP2305 ameliorates chronic stress-associated symptoms in Japanese medical students |
|
言語 |
en |
| 著者 |
西田, 憲生
サワダ, ダイスケ
桑野, 由紀
タナカ, ヒロキ
スガワラ, トモノリ
アオキ, ユメコ
フジワラ, シゲル
六反, 一仁
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Administration of Lactobacillus gasseri CP2305 for 4 weeks improved stress-associated behaviours in healthy young adults and clinical symptoms in patients with irritable bowel syndrome. The present study was designed to confirm the stress-relieving effects of heat-inactivated, washed CP2305 (paraprobiotic CP2305) on 69 sixth-year medical students (40 males and 29 females) preparing to take the national examination for medical practitioners. Administration of the paraprobiotic CP2305 for 12 weeks significantly improved sleep quality assessed by both the Pittsburgh Sleep Quality Index and a one-channel sleep electroencephalogram during the pre-examination period compared with that of the placebo administration. The paraprobiotic CP2305 administration also prevented increases in basal salivary cortisol release and expression of stress-responsive microRNAs (miR-144 and miR-144⁄). In addition to the improvement in parasympathetic nerve activity, the paraprobiotic CP2305 normalized the bowel habits under the stressful conditions. Based on these results, we propose that paraprobiotic CP2305 may be used as a para-psychobiotic. |
|
言語 |
en |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Lactobacillus gasseri CP2305 |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Chronic psychological stress |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Stress-related behaviours |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Sleep quality |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Stress-responsive microRNAs |
| 書誌情報 |
en : Journal of Functional Foods
巻 36,
p. 112-121,
発行日 2017-07-05
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
17564646 |
| 出版者 |
|
|
出版者 |
Elsevier |
|
言語 |
en |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
© 2017 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-NDlicense (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| EID |
|
|
識別子 |
344579 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
jff_36_112.pdf (604 KB)
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