| Item type |
文献 / Documents(1) |
| 公開日 |
2019-04-19 |
| アクセス権 |
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|
アクセス権 |
open access |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 出版社版DOI |
|
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|
関連識別子 |
https://doi.org/10.1253/circj.CJ-18-0017 |
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|
関連名称 |
10.1253/circj.CJ-18-0017 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Prognostic Value of Frailty and Diastolic Dysfunction in Elderly Patients |
| タイトル別表記 |
|
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その他のタイトル |
Frailty and Diastolic Dysfunction |
| 著者 |
楠瀬, 賢也
オオクシ, ユウイチロウ
山田, 博胤
ニシオ, ススム
トリイ, ユウタ
ヒラタ, ユキナ
西條, 良仁
伊勢, 孝之
山口, 浩司
八木, 秀介
添木, 武
若槻, 哲三
佐田, 政隆
|
| 抄録 |
|
|
内容記述 |
Background: High prevalence of frailty and of diastolic dysfunction (DD) in heart failure and high mortality in frail adults have been noted. We characterized frailty by quantifying differences on echocardiography, and assessed the added prognostic utility of frailty and DD grade in an elderly population.
Methods and Results: One hundred and ninety-one patients ≥65 years who had at least 1 cardiovascular risk factor were prospectively recruited for clinically indicated echocardiography at the present institute. Weight loss, exhaustion, and deficits in physical activity, gait speed, and handgrip strength were used to categorize patients as frail (≥3 features), intermediately frail (1 or 2 features), or non-frail (0 features). DD grade ≥2 was defined as severe. Frailty was associated with larger left atrial volume, smaller stroke volume, and worse DD grade after adjustment for age. In a period of 14 months, 29 patients (15%) had cardiovascular events. The addition of frailty score and severe DD significantly improved the prognostic power of a model containing male gender (model 1, male gender, χ2=6.4; model 2, model 1 plus frailty score, χ2=16.7, P=0.004; model 3, model 2 plus severe DD, χ2=25.5, P=0.015).
Conclusions: Both frailty and DD grade were significantly associated with future cardiovascular events in an elderly population with preserved ejection fraction and ≥1 risk factor of cardiovascular disease. |
| キーワード |
|
|
主題 |
Diastolic function |
| キーワード |
|
|
主題 |
Elderly patient |
| キーワード |
|
|
主題 |
Frailty |
| キーワード |
|
|
主題 |
Prognosis |
| 書誌情報 |
en : Circulation Journal
巻 82,
号 8,
p. 2103-2110,
発行日 2018-04-28
|
| 収録物ID |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13469843 |
| 収録物ID |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13474820 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11591968 |
| 出版者 |
|
|
出版者 |
The Japanese Circulation Society |
| EID |
|
|
識別子 |
339442 |
| 言語 |
|
|
言語 |
eng |
circj_82_8_2103.pdf (851 KB)
