| Item type |
文献 / Documents(1) |
| 公開日 |
2019-10-10 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
関連識別子 |
https://doi.org/10.2174/1568026618666180112163741 |
|
|
関連名称 |
10.2174/1568026618666180112163741 |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| タイトル |
|
|
タイトル |
Aurora Kinase Inhibitors in Head and Neck Cancer |
| 著者 |
Qi, Guangying
Liu, Jing
Mi, Sisi
常松, 貴明
Jin, Shengjian
Shao, Wenhua
Liu, Tian
石丸, 直澄
Tang, Bo
工藤, 保誠
|
| 抄録 |
|
|
内容記述 |
Aurora kinases are a group of serine/threonine kinases responsible for the regulation of mitosis. In recent years, with the increase in Aurora kinase-related research, the important role of Aurora kinases in tumorigenesis has been gradually recognized. Aurora kinases have been regarded as a new target for cancer therapy, resulting in the development of Aurora kinase inhibitors. The study and application of these small-molecule inhibitors, especially in combination with chemotherapy drugs, represents a new direction in cancer treatment. This paper reviews studies on Aurora kinases from recent years, including studies of their biological function, their relationship with tumor progression, and their inhibitors. |
| キーワード |
|
|
主題 |
Aurora kinases |
| キーワード |
|
|
主題 |
Mitosis |
| キーワード |
|
|
主題 |
Head and neck cancer |
| キーワード |
|
|
主題 |
Aurora kinase inhibitor |
| 書誌情報 |
en : Current Topics in Medicinal Chemistry
巻 18,
号 3,
p. 199-213,
発行日 2018
|
| 収録物ID |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
15680266 |
| 収録物ID |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
18734294 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11692499 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12814900 |
| 出版者 |
|
|
出版者 |
Bentham Science |
| EID |
|
|
識別子 |
335883 |
| 言語 |
|
|
言語 |
eng |
ctmc_18_3_199.pdf (1.18 MB)
