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Organic Chemistry Research on the Mechanistic Elucidation of Iron Acquisition in Barley
https://tokushima-u.repo.nii.ac.jp/records/2006669
https://tokushima-u.repo.nii.ac.jp/records/2006669b2f9b6be-9e4d-4e78-a722-37c61711705d
| 名前 / ファイル | ライセンス | アクション |
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bpb_41_10_1502.pdf (3.97 MB)
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| Item type | 文献 / Documents(1) | |||||||||||||||||
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| 公開日 | 2019-09-10 | |||||||||||||||||
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| アクセス権 | open access | |||||||||||||||||
| 資源タイプ | ||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||
| 出版社版DOI | ||||||||||||||||||
| 関連識別子 | https://doi.org/10.1248/bpb.b18-00070 | |||||||||||||||||
| 関連名称 | 10.1248/bpb.b18-00070 | |||||||||||||||||
| 出版タイプ | ||||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||
| タイトル | ||||||||||||||||||
| タイトル | Organic Chemistry Research on the Mechanistic Elucidation of Iron Acquisition in Barley | |||||||||||||||||
| 著者 |
難波, 康祐
× 難波, 康祐
WEKO
650
× ムラタ, ヨシコ
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| 内容記述 | An organic chemistry approach to the mechanistic elucidation of iron acquisition in graminaceous plants is introduced here. To elucidate this detailed mechanism using phytosiderophores, the efficient synthesis of 2’-deoxymugineic acid (DMA), a phytosiderophore of rice, was established. The synthetic DMA was confirmed to have similar iron transport activity to that of natural mugineic acid (MA). It was also revealed that the addition of synthetic DMA, along with iron, to a rice hydroponic solution enabled the rice to grow well even under an alkaline condition, and DMA clearly showed its high potential as a fertilizer to improve food production. On the other hand, the 2’-hydroxy group of MA was confirmed to serve as a point of introduction for labeling, allowing the synthesis of various mugineic acid derivatives as molecular probes. The incorporation of fluorescent mugineic acid into cells allowed them to be clearly observed by fluorescence confocal analysis, and this provided the first direct experimental evidence of transporter-mediated internalization of mugineic acid into cells. | |||||||||||||||||
| キーワード | ||||||||||||||||||
| 主題 | mugineic acid | |||||||||||||||||
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| 主題 | 2'-deoxymugineic acid | |||||||||||||||||
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| 主題 | mugineic acid–iron(III) complex transporter | |||||||||||||||||
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| 主題 | practical synthesis | |||||||||||||||||
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| 主題 | mugineic acid probe | |||||||||||||||||
| 書誌情報 |
en : Biological and Pharmaceutical Bulletin 巻 41, 号 10, p. 1502-1507, 発行日 2018-10-01 |
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| 収録物識別子タイプ | ISSN | |||||||||||||||||
| 収録物識別子 | 09186158 | |||||||||||||||||
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| 収録物識別子タイプ | ISSN | |||||||||||||||||
| 収録物識別子 | 13475215 | |||||||||||||||||
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| 収録物識別子タイプ | NCID | |||||||||||||||||
| 収録物識別子 | AA10885497 | |||||||||||||||||
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| 収録物識別子タイプ | NCID | |||||||||||||||||
| 収録物識別子 | AA11696048 | |||||||||||||||||
| 出版者 | ||||||||||||||||||
| 出版者 | The Pharmaceutical Society of Japan | |||||||||||||||||
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| 識別子 | 356296 | |||||||||||||||||
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| 言語 | eng | |||||||||||||||||
