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Polarization-resolved second-harmonic-generation imaging of dermal collagen fiber in prewrinkled and wrinkled skins of ultraviolet-B-exposed mouse
https://tokushima-u.repo.nii.ac.jp/records/2006677
https://tokushima-u.repo.nii.ac.jp/records/200667708871933-af38-49b7-a5e1-8c166e3f125d
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
jbo_24_3_031006.pdf (6.91 MB)
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| Item type | 文献 / Documents(1) | |||||||||||||||||||||||
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| 公開日 | 2019-09-11 | |||||||||||||||||||||||
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| アクセス権 | open access | |||||||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||||||
| 出版社版DOI | ||||||||||||||||||||||||
| 関連識別子 | https://doi.org/10.1117/1.JBO.24.3.031006 | |||||||||||||||||||||||
| 関連名称 | 10.1117/1.JBO.24.3.031006 | |||||||||||||||||||||||
| 出版タイプ | ||||||||||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||||||
| タイトル | ||||||||||||||||||||||||
| タイトル | Polarization-resolved second-harmonic-generation imaging of dermal collagen fiber in prewrinkled and wrinkled skins of ultraviolet-B-exposed mouse | |||||||||||||||||||||||
| 著者 |
フクシマ, シュウイチロウ
× フクシマ, シュウイチロウ
× ヨネツ, マコト
× 安井, 武史
WEKO
462
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| 内容記述 | Skin wrinkling is a typical symptom of cutaneous photoaging; however, the skin wrinkling depends on not only the actual age but also exposure history to ultraviolet B (UVB) rays in individuals. Therefore, there is considerable need for its assessment technique in vivo in skin cosmetics and antiaging dermatology. Wrinkles always appear as linear grooves in the skin, and dermal collagen fibers play an important role to determine the morphology and mechanical properties of the skin. Therefore, an optical probe sensitive to dermal collagen fiber and its orientation will be useful. Polarization-resolved second-harmonic-generation (SHG) microscopy is a promising approach for in vivo evaluation of collagen fiber orientation because the efficiency of SHG light is sensitive to collagen fiber orientation when the incident light is linearly polarized. We investigate orientation change of dermal collagen fiber in prewrinkled and wrinkled skins of the UVB-exposed mouse model using polarization-resolved SHG microscopy. A polarization anisotropic image of the SHG light indicates that the change of collagen fiber orientation starts in the prewrinkled skin of UVB-exposed mice, then the wrinkle appears. Furthermore, the dominant direction of collagen fiber orientation in the prewrinkled skin is significantly parallel to the wrinkle direction in the wrinkled skin. This result implies that the change of collagen fiber orientation is a trigger of wrinkling in cutaneous photoaging. | |||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||
| 主題 | skin | |||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||
| 主題 | photoaging | |||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||
| 主題 | collagen | |||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||
| 主題 | wrinkle | |||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||
| 主題 | orientation | |||||||||||||||||||||||
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| 主題 | second-harmonic-generation microscopy | |||||||||||||||||||||||
| 書誌情報 |
en : Journal of Biomedical Optics 巻 24, 号 3, p. 031006, 発行日 2018-09-06 |
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| 収録物識別子タイプ | ISSN | |||||||||||||||||||||||
| 収録物識別子 | 10833668 | |||||||||||||||||||||||
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| 収録物識別子タイプ | ISSN | |||||||||||||||||||||||
| 収録物識別子 | 15602281 | |||||||||||||||||||||||
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| 収録物識別子タイプ | NCID | |||||||||||||||||||||||
| 収録物識別子 | AA11237889 | |||||||||||||||||||||||
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| 収録物識別子タイプ | NCID | |||||||||||||||||||||||
| 収録物識別子 | AA11953151 | |||||||||||||||||||||||
| 出版者 | ||||||||||||||||||||||||
| 出版者 | SPIE | |||||||||||||||||||||||
| 権利情報 | ||||||||||||||||||||||||
| 権利情報 | © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI. [DOI: 10.1117/1.JBO.24.3.031006] | |||||||||||||||||||||||
| EID | ||||||||||||||||||||||||
| 識別子 | 354834 | |||||||||||||||||||||||
| 言語 | ||||||||||||||||||||||||
| 言語 | eng | |||||||||||||||||||||||
