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Calprotectin and cross-linked N-telopeptides of type I collagen levels in crevicular fluid from implant sites with peri-implant diseases : a pilot study
https://tokushima-u.repo.nii.ac.jp/records/2006970
https://tokushima-u.repo.nii.ac.jp/records/2006970f38063fa-7db5-4edd-a62d-c36f3de12771
名前 / ファイル | ライセンス | アクション |
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Item type | 文献 / Documents(1) | |||||||||||||||||||||||||||||
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公開日 | 2019-11-15 | |||||||||||||||||||||||||||||
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アクセス権 | open access | |||||||||||||||||||||||||||||
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資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||||||||||
資源タイプ | journal article | |||||||||||||||||||||||||||||
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識別子タイプ | DOI | |||||||||||||||||||||||||||||
関連識別子 | https://doi.org/10.1186/s40729-018-0138-2 | |||||||||||||||||||||||||||||
言語 | ja | |||||||||||||||||||||||||||||
関連名称 | 10.1186/s40729-018-0138-2 | |||||||||||||||||||||||||||||
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出版タイプ | VoR | |||||||||||||||||||||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||||||||||||
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タイトル | Calprotectin and cross-linked N-telopeptides of type I collagen levels in crevicular fluid from implant sites with peri-implant diseases : a pilot study | |||||||||||||||||||||||||||||
言語 | en | |||||||||||||||||||||||||||||
著者 |
坂本, 英次郎
× 坂本, 英次郎
× 木戸, 理恵
WEKO
1006
× 友竹, 偉則
WEKO
1709
× 内藤, 禎人× 石田, 雄一
WEKO
503
× 木戸, 淳一 |
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内容記述タイプ | Abstract | |||||||||||||||||||||||||||||
内容記述 | Background: Peri-implant crevicular fluid (PICF) contains calprotectin and NTx, which are markers for inflammation and bone resorption, respectively. The aims of this pilot study were to compare calprotectin and NTx levels in PICF from implant sites with or without peri-implant diseases and to evaluate the usefulness of calprotectin and NTx as diagnostic markers for peri-implant diseases. Methods: Thirty-five patients with dental implants participated in this pilot study. PICF samples were collected from peri-implant disease sites (n = 40) and non-diseased (healthy) sites (n = 34) after clinical indicators including probing depth (PD), bleeding on probing (BOP), gingival index (GI), and bone loss (BL) rate were investigated. Calprotectin and NTx amounts in PICF were measured using their respective ELISA kits and then compared between diseased and healthy samples. The relationship between PICF calprotectin or NTx levels and clinical indicator levels was investigated. A receiver operating characteristic (ROC) curve analysis of calprotectin and NTx was performed to predict peri-implant diseases. Results: Calprotectin and NTx levels in PICF were significantly higher from peri-implant disease sites than from healthy sites. PICF calprotectin amounts correlated with PD, and its levels were significantly higher in the GI-1 and GI-2 groups than in the GI-0 group. PICF NTx amounts correlated with PD and the BL rate. ROC curves indicated that PICF calprotectin and NTx are useful biomarkers for peri-implant diseases. Conclusions: Calprotectin and NTx in PICF have potential as biomarkers for the diagnosis of peri-implant diseases. |
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言語 | en | |||||||||||||||||||||||||||||
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言語 | en | |||||||||||||||||||||||||||||
主題Scheme | Other | |||||||||||||||||||||||||||||
主題 | Calprotectin | |||||||||||||||||||||||||||||
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言語 | en | |||||||||||||||||||||||||||||
主題Scheme | Other | |||||||||||||||||||||||||||||
主題 | NTx | |||||||||||||||||||||||||||||
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言語 | en | |||||||||||||||||||||||||||||
主題Scheme | Other | |||||||||||||||||||||||||||||
主題 | Peri-implant crevicular fluid | |||||||||||||||||||||||||||||
キーワード | ||||||||||||||||||||||||||||||
言語 | en | |||||||||||||||||||||||||||||
主題Scheme | Other | |||||||||||||||||||||||||||||
主題 | Peri-implant diseases | |||||||||||||||||||||||||||||
書誌情報 |
en : International Journal of Implant Dentistry 巻 4, p. 26, 発行日 2018-09-13 |
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収録物識別子タイプ | ISSN | |||||||||||||||||||||||||||||
収録物識別子 | 21984034 | |||||||||||||||||||||||||||||
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出版者 | Springer | |||||||||||||||||||||||||||||
言語 | en | |||||||||||||||||||||||||||||
権利情報 | ||||||||||||||||||||||||||||||
言語 | en | |||||||||||||||||||||||||||||
権利情報 | © The Author(s). 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. | |||||||||||||||||||||||||||||
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識別子 | 355649 | |||||||||||||||||||||||||||||
識別子タイプ | URI | |||||||||||||||||||||||||||||
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言語 | eng |