| Item type |
文献 / Documents(1) |
| 公開日 |
2019-11-29 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
関連識別子 |
https://doi.org/10.1111/jdi.12582 |
|
|
関連名称 |
10.1111/jdi.12582 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Advanced glycation end‐products are a risk for muscle weakness in Japanese patients with type 1 diabetes |
| タイトル別表記 |
|
|
その他のタイトル |
Sarcopenia and AGEs in type 1 diabetes |
| 著者 |
森, 博康
黒田, 暁生
アラキ, ミチコ
スズキ, レイコ
谷口, 諭
田蒔, 基行
アケヒ, ユウコ
松久, 宗英
|
| 抄録 |
|
|
内容記述 |
Accumulation of advanced glycation end-products (AGEs) is thought to contribute to muscle weakness in a diabetic animal model. Skin autofluorescence is a proposed marker for accumulation of AGEs in the skin. We aimed to investigate the relationship between AGEs accumulation, sarcopenia and muscle function of Japanese patients with type 1 diabetes. A total of 36 patients with type 1 diabetes participated in the present cross-sectional study. Sarcopenia parameters (skeletal muscle mass index and knee extension strength) were compared with subcutaneous AGEs accumulation using skin autofluorescence. The prevalence of sarcopenia and impaired knee extension strength was 16.6% (men 0.0%, women 22.2%) and 47.2% (men 22.2%, women 55.6%), respectively. Knee extension strength was negatively correlated with skin autofluorescence (r² = 0.14, P < 0.05), but not with skeletal muscle mass index. In conclusion, the AGEs accumulation might be one of the reasons of impaired lower limb muscle function in Japanese patients with type 1 diabetes. |
| キーワード |
|
|
主題 |
Advanced glycation end-products |
| キーワード |
|
|
主題 |
Sarcopenia |
| キーワード |
|
|
主題 |
Type 1 diabetes |
| 書誌情報 |
en : Journal of Diabetes Investigation
巻 8,
号 3,
p. 377-382,
発行日 2016-10-11
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
20401124 |
| 出版者 |
|
|
出版者 |
Asian Association for the Study of Diabetes |
| 出版者 |
|
|
出版者 |
John Wiley & Sons Australia |
| 権利情報 |
|
|
権利情報 |
© 2016 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, LtdThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
| EID |
|
|
識別子 |
320962 |
| 言語 |
|
|
言語 |
eng |
jdi_8_3_377.pdf (221 KB)
.png)
