Item type |
文献 / Documents(1) |
公開日 |
2020-03-17 |
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アクセス権 |
open access |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
出版社版DOI |
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関連識別子 |
https://doi.org/10.1371/journal.pone.0213110 |
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関連名称 |
10.1371/journal.pone.0213110 |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
タイトル |
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タイトル |
Central serous chorioretinopathy with and without steroids : A multicenter survey |
タイトル別表記 |
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その他のタイトル |
CSC with and without steroids |
著者 |
アラキ, タカシ
イシカワ, ヒロト
イワサキ, チハル
仁木, 昌徳
三田村, 佳典
スギモト, マサヒコ
コンドウ, ミネオ
木下, 貴正
ニシ, トモ
ウエダ, テツオ
カトウ, アキ
ヤスカワ, ツトム
タカムラ, ヨシヒロ
ゴミ, フミ
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抄録 |
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内容記述 |
We investigated the rates of the use of steroids in Japanese central serous chorioretinopathy (CSC) cases and differences in the characteristics of CSC with and without steroids. A total of 538 eyes of 477 patients diagnosed with CSC, with 3 months or more of follow-up between April 2013 and June 2017 at 8 institutions. Patients with CSC with more than 3 months of follow-up were identified by OCT and fluorescein angiography at 8 institutions. Data collected included patient demographics, history of corticosteroid medication and smoking, spherical errors, findings of angiography, subfoveal choroidal thickness, and changes through the follow-up period. Differences in these findings were analyzed in cases with and without corticosteroid treatment. Among the 477 patients (344 men,133 women), 74 (15.5%) (39 men, 35 women) underwent current or prior steroid treatment. Cases with steroids were higher age (p = 0.0403) and showed no male prevalence, more bilateral involvement (p < 0.0001), and the affected eyes had multiple pigment epithelial detachment (p <0.0001), more fluorescein leakage sites (p < 0.0001), greater choroidal thickness (p = 0.0287) and a higher recurrence rate (p = 0.0412). Steroids can cause severer CSC through an effect on choroidal vessels and an impairment of retinal pigment epithelium. |
書誌情報 |
en : PLOS ONE
巻 14,
号 2,
p. e0213110,
発行日 2019-02-28
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収録物ID |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
19326203 |
出版者 |
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出版者 |
PLOS |
権利情報 |
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権利情報 |
© 2019 Araki et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
EID |
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識別子 |
351687 |
言語 |
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言語 |
eng |