| アイテムタイプ |
文献 / Documents(1) |
| 公開日 |
2020-03-12 |
| アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 出版社版DOI |
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関連識別子 |
https://doi.org/10.1111/j.1349-7006.1991.tb01916.x |
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関連名称 |
10.1111/j.1349-7006.1991.tb01916.x |
| 出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
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タイトル |
Allele Loss on Chromosome 11 in a Pituitary Tumor from a Patient with Multiple Endocrine Neoplasia Type 1 |
| タイトル別表記 |
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その他のタイトル |
Allele Loss in MEN 1-associated Pituitary Tumor |
| 著者 |
吉本, 勝彦
イワハナ, ヒロユキ
クボ, カツユキ
齋藤, 史郎
板倉, 光夫
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| 抄録 |
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内容記述 |
We have examined the allele loss of chromosome 11 in a pituitary tumor from a patient with familial multiple endocrine neoplasia type 1 (MEN 1). The extensive loss of chromosome 11, including loci of D11S149, HRAS1 and F2, was detected by the loss of heterozygosity. All of the lost alleles of these loci were transmitted from the unaffected father and not from an affected mother. This is the first evidence of allele loss of chromosome 11 in a pituitary tumor of MEN 1 and supports the idea that similar allelic deletion of MEN1 locus on chromosome 11 is the common genetic basis for tumorigenesis in the pituitary, endocrine pancreas, and parathyroid gland in MEN 1. |
| キーワード |
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主題 |
Allele loss |
| キーワード |
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主題 |
Chromosome 11 |
| キーワード |
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主題 |
Pituitary tumor |
| キーワード |
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主題 |
Multiple endocrine neoplasia type 1 |
| 書誌情報 |
en : Japanese Journal of Cancer Research
巻 82,
号 8,
p. 886-889,
発行日 1991-08
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| 収録物ID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA00690844 |
| 出版者 |
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出版者 |
Japanese Cancer Association |
| 出版者 |
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出版者 |
John Wiley & Sons |
| EID |
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識別子 |
71323 |
| 言語 |
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言語 |
eng |
jjcr_82_8_886.pdf (234 KB)
