| Item type |
文献 / Documents(1) |
| 公開日 |
2021-02-08 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
関連識別子 |
https://doi.org/10.2169/internalmedicine.55.7359 |
|
|
関連名称 |
10.2169/internalmedicine.55.7359 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Suppression of the Hypothalamic-pituitary-adrenal Axis by Maximum Androgen Blockade in a Patient with Prostate Cancer |
| 著者 |
近藤, 剛史
遠藤, 逸朗
オオグロ, ユカリ
森本, 佳奈
倉橋, 清衛
吉田, 守美子
黒田, 暁生
粟飯原, 賢一
松久, 宗英
安倍, 正博
福本, 誠二
|
| 抄録 |
|
|
内容記述 |
A 78-year-old Japanese man showed suppression of the hypothalamic-pituitary-adrenal axis during maximum androgen blockade (MAB) therapy including chlormadinone acetate (CMA) for prostate cancer. After stopping the MAB therapy, both the basal ACTH level and the response to CRH recovered. While no reports have indicated that CMA suppresses the hypothalamic-pituitary-adrenal axis in patients with prostate cancer, CMA has been shown to inhibit this axis in animals. These observations suggest that we must monitor the hypothalamic-pituitary-adrenal axis in patients treated with CMA, especially under stressful conditions. |
| キーワード |
|
|
主題 |
hypothalamic-pituitary-adrenal axis |
| キーワード |
|
|
主題 |
adrenal insufficiency |
| キーワード |
|
|
主題 |
chlormadinone acetate |
| キーワード |
|
|
主題 |
prostate cancer |
| 書誌情報 |
en : Internal Medicine
巻 55,
号 24,
p. 3623-3626,
発行日 2016-12-15
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13497235 |
| 出版者 |
|
|
出版者 |
The Japanese Society of Internal Medicine |
| 権利情報 |
|
|
権利情報 |
The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
| EID |
|
|
識別子 |
322685 |
| 言語 |
|
|
言語 |
eng |
internalmedicine_55_24_3623.pdf (133 KB)
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