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Glucose-responsive hydrogel electrode for biocompatible glucose transistor
https://tokushima-u.repo.nii.ac.jp/records/2007420
https://tokushima-u.repo.nii.ac.jp/records/20074207281649f-2980-44b0-9cdd-0560488f96af
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
stam_18_1_26.pdf (1.46 MB)
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| Item type | 文献 / Documents(1) | |||||||||||
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| 公開日 | 2020-04-30 | |||||||||||
| アクセス権 | ||||||||||||
| アクセス権 | open access | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | journal article | |||||||||||
| 出版社版DOI | ||||||||||||
| 関連識別子 | https://doi.org/10.1080/14686996.2016.1257344 | |||||||||||
| 関連名称 | 10.1080/14686996.2016.1257344 | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Glucose-responsive hydrogel electrode for biocompatible glucose transistor | |||||||||||
| 著者 |
加治佐, 平
× 加治佐, 平× サカタ, トシヤ
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| 抄録 | ||||||||||||
| 内容記述 | In this paper, we propose a highly sensitive and biocompatible glucose sensor using a semiconductor-based field effect transistor (FET) with a functionalized hydrogel. The principle of the FET device contributes to the easy detection of ionic charges with high sensitivity, and the hydrogel coated on the electrode enables the specific detection of glucose with biocompatibility. The copolymerized hydrogel on the Au gate electrode of the FET device is optimized by controlling the mixture ratio of biocompatible 2-hydroxyethylmethacrylate (HEMA) as the main monomer and vinylphenylboronic acid (VPBA) as a glucose-responsive monomer. The gate surface potential of the hydrogel FETs shifts in the negative direction with increasing glucose concentration from 10 μM to 40 mM, which results from the increase in the negative charges on the basis of the diol-binding of PBA derivatives with glucose molecules in the hydrogel. Moreover, the hydrogel coated on the gate suppresses the signal noise caused by the nonspecific adsorption of proteins such as albumin. The hydrogel FET can serve as a highly sensitive and biocompatible glucose sensor in in vivo or ex vivo applications such as eye contact lenses and sheets adhering to the skin. | |||||||||||
| キーワード | ||||||||||||
| 主題 | Field effect transistor | |||||||||||
| キーワード | ||||||||||||
| 主題 | hydrogel | |||||||||||
| キーワード | ||||||||||||
| 主題 | phenylboronic acid | |||||||||||
| キーワード | ||||||||||||
| 主題 | glucose | |||||||||||
| キーワード | ||||||||||||
| 主題 | biocompatibility | |||||||||||
| 書誌情報 |
en : Science and Technology of Advanced Materials 巻 18, 号 1, p. 26-33, 発行日 2017-01-09 |
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| 収録物ID | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 14686996 | |||||||||||
| 収録物ID | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 18785514 | |||||||||||
| 収録物ID | ||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||
| 収録物識別子 | AA11561821 | |||||||||||
| 出版者 | ||||||||||||
| 出版者 | Taylor & Francis | |||||||||||
| 出版者 | ||||||||||||
| 出版者 | National Institute for Materials Science | |||||||||||
| 権利情報 | ||||||||||||
| 権利情報 | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||||||||
| EID | ||||||||||||
| 識別子 | 363928 | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
