| Item type |
文献 / Documents(1) |
| 公開日 |
2020-11-24 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.3389/fpsyt.2018.00691 |
|
|
言語 |
ja |
|
|
関連名称 |
10.3389/fpsyt.2018.00691 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Altered Gamma-Band Activity as a Potential Biomarker for the Recurrence of Major Depressive Disorder |
|
言語 |
en |
| タイトル別表記 |
|
|
その他のタイトル |
Altered Gamma-Band Activity in Recovered Depression |
|
言語 |
en |
| 著者 |
山本, 哲也
スガヤ, ナギサ
Siegle, Greg J.
クマノ, ヒロアキ
シマダ, ヒロノリ
Machado, Sergio
Murillo-Rodriguez, Eric
Rocha, Nuno B.
Nardi, Antonio E.
タカムラ, マサヒロ
オカモト, ヤスマサ
ヤマワキ, シゲト
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Background: The neurophysiological mechanisms of cognitive reactivity, the primary vulnerability factor of major depressive disorder (MDD) recurrence, remain unclear in individuals with recovered MDD (rMDD). Because gamma-band responses (GBRs) can be used to measure cognitive processing, they may also be useful for elucidating the mechanisms underlying cognitive reactivity. Identifying these mechanisms may permit the development of an index for predicting and preempting MDD recurrence. Here, to identify the neurophysiological mechanisms of cognitive reactivity, we examined the characteristics of the GBRs evoked/induced by emotional words in participants with and without rMDD after inducing a negative mood.
Methods: Thirty-three healthy control participants and 18 participants with rMDD completed a lexical emotion identification task during electroencephalography along with assessments of cognitive reactivity after negative mood induction.
Results: No between-group differences were identified for the task reaction times; however, the rMDD group had significantly higher cognitive reactivity scores than did the control group. Furthermore, the power of late GBRs to positive words was significantly greater in the rMDD group, with the greater power of late GBRs being related to higher cognitive reactivity.
Limitations: Considering the population studied, our findings cannot be completely generalized to populations other than adolescents, people with rMDD, and those without a history of co-morbid disorders and early life stress.
Conclusions: Our findings indicate that the dysfunction of neural circuits related to higher-order processes like memory and attention might underlie cognitive reactivity. Altered late GBRs to positive information may be persistent biomarkers of the depression recurrence risk. |
|
言語 |
en |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
cognitive reactivity |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
EEG |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
depression |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
gamma |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
mood induction |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
recovery |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
biomarker |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
memory |
| 書誌情報 |
en : Frontiers in Psychiatry
巻 9,
p. 691,
発行日 2018-12-12
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
16640640 |
| 出版者 |
|
|
出版者 |
Frontiers Media S.A. |
|
言語 |
en |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
Copyright © 2018 Yamamoto, Sugaya, Siegle, Kumano, Shimada, Machado, Murillo-Rodriguez, Rocha, Nardi, Takamura, Okamoto and Yamawaki. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| EID |
|
|
識別子 |
358139 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
fpsyt_9_691.pdf (806 KB)
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