| Item type |
文献 / Documents(1) |
| 公開日 |
2020-11-26 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.3748/wjg.v22.i3.1289 |
|
|
言語 |
ja |
|
|
関連名称 |
10.3748/wjg.v22.i3.1289 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Recent advances in photodynamic diagnosis of gastric cancer using 5-aminolevulinic acid |
|
言語 |
en |
| タイトル別表記 |
|
|
その他のタイトル |
Advances in 5-ALA-PDD of gastric cancer |
|
言語 |
en |
| 著者 |
コイズミ, ノリアキ
ハラダ, ヨシノリ
南川, 丈夫
タナカ, ヒデオ
オオツジ, エイゴ
タカマツ, テツロウ
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Photodynamic diagnosis based on 5-aminolevulinic acid-induced protoporphyrin IX has been clinically applied in many fields based upon its evidenced efficacy and adequate safety. In order to establish a personalized medicine approach for treating gastric cancer patients, rapid intraoperative detection of malignant lesions has become important. Feasibility of photodynamic diagnosis using 5-aminolevulinic acid for gastric cancer patients has been investigated, especially for the detection of peritoneal dissemination and lymph node metastasis. This method enables intraoperative real-time fluorescence detection of peritoneal dissemination, exhibiting higher sensitivity than white light observation without histopathological examination. The method also enables detection of metastatic foci within excised lymph nodes, exhibiting a diagnostic accuracy comparable to that of a current molecular diagnostics technique. Although several complicating issues still need to be resolved, such as the effect of tissue autofluorescence and the insufficient depth penetration of excitation light, this simple and rapid method has the potential to become a useful diagnostic tool for gastric cancer, as well as urinary bladder cancer and glioma. |
|
言語 |
en |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Gastric cancer |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Photodynamic diagnosis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
5-aminolevulinic acid |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Protoporphyrin IX |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Lymph node metastasis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Personalized medicine |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Peritoneal dissemination |
| 書誌情報 |
en : World Journal of Gastroenterology
巻 22,
号 3,
p. 1289-1296,
発行日 2016-01-21
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
10079327 |
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
22192840 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11690631 |
| 出版者 |
|
|
出版者 |
Baishideng Publishing Group Inc. |
|
言語 |
en |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| EID |
|
|
識別子 |
313646 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
wjg_22_3_1289.pdf (1.31 MB)
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