| Item type |
文献 / Documents(1) |
| 公開日 |
2020-11-27 |
| アクセス権 |
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アクセス権 |
open access |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 出版社版DOI |
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|
関連識別子 |
https://doi.org/10.1186/s41021-016-0042-z |
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|
関連名称 |
10.1186/s41021-016-0042-z |
| 出版タイプ |
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|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
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|
タイトル |
Oral environment and cancer |
| 著者 |
工藤, 保誠
タダ, ヒデスケ
藤原, 奈津美
タダ, ヨシコ
常松, 貴明
三宅, 洋一郎
石丸, 直澄
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| 抄録 |
|
|
内容記述 |
Cancer is now the leading cause of death in Japan. A rapid increase in cancer mortality is expected as Japan is facing a super-aged society. Many causes of cancer are known to be closely linked to life style factors, such as smoking, drinking, and diet. The oral environment is known to be involved in the pathogenesis and development of various diseases such as bronchitis, pneumonia, diabetes, heart disease, and dementia. Because the oral cavity acts as the bodily entrance for air and food, it is constantly exposed to foreign substances, including bacteria and viruses. A large number of bacteria are endemic to the oral cavity, and indigenous oral flora act to prevent the settlement of foreign bacteria. The oral environment is influenced by local factors, including dental plaque, tartar, teeth alignment, occlusion, an incompatible prosthesis, and bad lifestyle habits, and systemic factors, including smoking, consumption of alcohol, irregular lifestyle and eating habits, obesity, stress, hormones, and heredity. It has recently been revealed that the oral environment is associated with cancer. In particular, commensal bacteria in the oral cavity are involved in the development of cancer. Moreover, Candida, human papilloma virus and Epstein-Barr virus as well as commensal bacteria have been reported to be associated with the pathogenesis of cancer. In this review, we introduce recent findings of the correlation between the oral environment and cancer. |
| キーワード |
|
|
主題 |
Cancer |
| キーワード |
|
|
主題 |
Oral environment |
| キーワード |
|
|
主題 |
Bacteria |
| キーワード |
|
|
主題 |
Candida |
| キーワード |
|
|
主題 |
Human papilloma virus |
| キーワード |
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|
主題 |
Epstein-Barr virus |
| 書誌情報 |
en : Genes and Environment
巻 38,
p. 13,
発行日 2016-08-01
|
| 収録物ID |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
18807062 |
| 収録物ID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA1212552X |
| 出版者 |
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|
出版者 |
BioMed Central |
| 出版者 |
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|
出版者 |
Springer Nature |
| 権利情報 |
|
|
権利情報 |
© 2016 Kudo et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| EID |
|
|
識別子 |
321004 |
| 言語 |
|
|
言語 |
eng |
genenv_38_13.pdf (742 KB)
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