WEKO3
アイテム
Jelly-type carbohydrate supplement in healthy subjects suppresses the catabolism of adipose tissue and muscle protein and improves their satisfactions
https://tokushima-u.repo.nii.ac.jp/records/2007595
https://tokushima-u.repo.nii.ac.jp/records/200759588c58d0f-1df1-4959-949a-159b44e110f8
| 名前 / ファイル | ライセンス | アクション |
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k3357_abstract_review.pdf (187 KB)
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k3357_fulltext.pdf (657 KB)
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| Item type | 文献 / Documents(1) | |||||||||||||||||||||||
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| 公開日 | 2020-05-14 | |||||||||||||||||||||||
| アクセス権 | ||||||||||||||||||||||||
| アクセス権 | open access | |||||||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||||||||||||||||
| 資源タイプ | doctoral thesis | |||||||||||||||||||||||
| 出版社版DOI | ||||||||||||||||||||||||
| 関連識別子 | https://doi.org/10.1016/j.yclnex.2018.04.002 | |||||||||||||||||||||||
| 関連名称 | 10.1016/j.yclnex.2018.04.002 | |||||||||||||||||||||||
| 出版タイプ | ||||||||||||||||||||||||
| 出版タイプ | NA | |||||||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_be7fb7dd8ff6fe43 | |||||||||||||||||||||||
| タイトル | ||||||||||||||||||||||||
| タイトル | Jelly-type carbohydrate supplement in healthy subjects suppresses the catabolism of adipose tissue and muscle protein and improves their satisfactions | |||||||||||||||||||||||
| タイトル別表記 | ||||||||||||||||||||||||
| その他のタイトル | 健康成人におけるゼリータイプの炭水化物サプリメント摂取は脂肪組織と筋蛋白質の異化を抑制し満足度を改善した | |||||||||||||||||||||||
| 著者 |
大山, 拓朗
× 大山, 拓朗× 角田, 奈美
WEKO
454
× 箕田, 直治× 川人, 伸次
WEKO
1644
× 田中, 克哉
WEKO
1645
× 堤, 保夫 |
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| 抄録 | ||||||||||||||||||||||||
| 内容記述 | Background & aims: Many studies have reported the effects of preoperative clear fluid carbohydrate supplements; however, few studies have reported the effects of preoperative jelly-type carbohydrate supplements. This study aimed to assess the effect of a jelly-type oral nutritional supplement (ONS) on metabolism, redox balance by using various surrogate markers and to evaluate its excretion from the stomach. Methods: This study was conducted according to a crossover design. Participants underwent a control experiment whereby they fasted after dinner and only ingested water until the experiment. The remaining participants underwent an ONS experiment whereby they ingested 400 g of ONS before bed and another 400 g at 7:00 am. Blood samples were collected at 9:00 am. After a break of at least 24 h, participants underwent the alternate experiment. Results: Thirty minutes after intake of jelly, the gastric antrum appeared flat (the same result as that at baseline) on ultrasonography. The ONS group showed significantly lower serum free fatty acid levels (100 μEq/L, p = 0.027, vs. 327 μEq/L, n = 6), total ketone bodies levels, 3-MH/creatinine levels, and oxidative stress surrogate markers. Serum insulin levels were significantly higher and participant's satisfaction was improved in the ONS group. Conclusions: We have the limitations of our methodologies as surrogate markers, compared with direct measurement of lipolysis, proteolysis and redox balance regulation. But Jelly-type ONS suppresses the catabolism of adipose tissue and muscle protein, decreases oxidative stress and improves patient satisfaction in healthy participants, without any increased risk of aspiration. |
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| キーワード | ||||||||||||||||||||||||
| 主題 | Crossover design | |||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||
| 主題 | Jelly-type oral nutritional supplement | |||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||
| 主題 | Metabolism | |||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||
| 主題 | Antioxidation | |||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||
| 主題 | ERAS | |||||||||||||||||||||||
| 書誌情報 |
en : Clinical Nutrition Experimental 巻 19, p. 1-11, 発行日 2018-04-10 |
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| 収録物識別子タイプ | ISSN | |||||||||||||||||||||||
| 収録物識別子 | 23529393 | |||||||||||||||||||||||
| 出版者 | ||||||||||||||||||||||||
| 出版者 | Elsevier | |||||||||||||||||||||||
| 出版者 | ||||||||||||||||||||||||
| 出版者 | European Society for Clinical Nutrition and Metabolism | |||||||||||||||||||||||
| 備考 | ||||||||||||||||||||||||
| 値 | 内容要旨・審査要旨・論文本文の公開 本論文は，著者Takuro Oyamaの学位論文として提出され，学位審査・授与の対象となっている。 学位授与者所属 : 徳島大学大学院医科学教育部（医学専攻） |
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| 権利情報 | ||||||||||||||||||||||||
| 権利情報 | © 2018 The Authors. Published by Elsevier Ltd on behalf of European Society for Clinical Nutrition and Metabolism. This is an open access article under the CC BY-NC-ND license. | |||||||||||||||||||||||
| EID | ||||||||||||||||||||||||
| 識別子 | 358038 | |||||||||||||||||||||||
| 言語 | ||||||||||||||||||||||||
| 言語 | eng | |||||||||||||||||||||||
| 報告番号 | ||||||||||||||||||||||||
| 学位授与番号 | 甲第3357号 | |||||||||||||||||||||||
| 学位記番号 | ||||||||||||||||||||||||
| 値 | 甲医第1440号 | |||||||||||||||||||||||
| 学位授与年月日 | ||||||||||||||||||||||||
| 学位授与年月日 | 2020-03-23 | |||||||||||||||||||||||
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| 学位名 | 博士（医学） | |||||||||||||||||||||||
| 学位授与機関 | ||||||||||||||||||||||||
| 学位授与機関名 | 徳島大学 | |||||||||||||||||||||||
