| Item type |
文献 / Documents(1) |
| 公開日 |
2020-07-17 |
| アクセス権 |
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|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.3389/fneur.2018.00622 |
|
|
言語 |
ja |
|
|
関連名称 |
10.3389/fneur.2018.00622 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Visual Target Strategies in Infantile Nystagmus Patients With Horizontal Jerk Waveform |
|
言語 |
en |
| タイトル別表記 |
|
|
その他のタイトル |
Viewing Targets in Infantile Nystagmus |
|
言語 |
en |
| 著者 |
イマイ, タカオ
タキモト, ヤスミツ
オクムラ, トモコ
ヒガシ シンガイ, カヨコ
武田, 憲昭
キタムラ, コウジ
カルビ, ブカサ
フジカド, タカシ
ヒロタ, マサカズ
ミドウ, ヨシヒロ
ナカマエ, コウジ
イノハラ, ヒデノリ
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
The aim of this study was to propose a new pathophysiological hypothesis for involuntary eye oscillation in infantile nystagmus (IN): patients with IN exhibit impaired gaze fixation, horizontal smooth pursuit and optokinetic nystagmus (OKN) and use saccadic eye movements for these underlying impairments. In order to induce saccades, they make enough angle between gaze and target by precedent exponential slow eye movements. IN consists of the alternate appearance of the saccade and the slow eye movements. Unlike most previous theories, IN is therefore considered a necessary strategy allowing for better vision and not an obstacle to clear vision. In five patients with IN, eye movements were analyzed during the smooth pursuit test, saccadic eye movement test, OKN test and vestibulo-ocular reflex (VOR) test. Their gaze fixation, horizontal smooth pursuit, OKN and the last half of the slow phase of VOR were impaired. The lines obtained by connection of the end eye positions of fast phase of nystagmus coincided with the trajectories of targets. The findings indicate that patients followed the target by the fast but not the slow phase of nystagmus, which supports our hypothesis. By setting the direction of slow phase of nystagmus opposite to the direction of the OKN stimulation, enough angle can be effectively made between the gaze and target for the induction of saccade. This is the mechanism of reversed OKN response. In darkness and when eyes are closed, IN weakens because there is no visual target and neither the saccade for catching up the target or slow phase for induction of the saccade is needed. |
|
言語 |
en |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
infantile nystagmus |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
saccade |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
three-dimensional analysis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
optokinetic nystagmus |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
vestibulo-ocular reflex |
| 書誌情報 |
en : Frontiers in Neurology
巻 9,
p. 622,
発行日 2018-07-30
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
16642295 |
| 出版者 |
|
|
出版者 |
Frontiers Media S.A. |
|
言語 |
en |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
© 2018 Imai, Takimoto, Okumura, Higashi-Shingai, Takeda, Kitamura, Kalubi, Fujikado, Hirota, Midoh, Nakamae and Inohara. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| EID |
|
|
識別子 |
365505 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
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