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The role of ATP in sleep regulation
https://tokushima-u.repo.nii.ac.jp/records/2007839
https://tokushima-u.repo.nii.ac.jp/records/200783981f22f72-f406-4ca1-aeef-1966830719eb
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
fneur_2_87.pdf (594 KB)
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| Item type | 文献 / Documents(1) | |||||||||||
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| 公開日 | 2020-07-17 | |||||||||||
| アクセス権 | ||||||||||||
| アクセス権 | open access | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | journal article | |||||||||||
| 出版社版DOI | ||||||||||||
| 関連識別子 | https://doi.org/10.3389/fneur.2011.00087 | |||||||||||
| 関連名称 | 10.3389/fneur.2011.00087 | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| タイトル | ||||||||||||
| タイトル | The role of ATP in sleep regulation | |||||||||||
| タイトル別表記 | ||||||||||||
| その他のタイトル | ATP and sleep | |||||||||||
| 著者 |
近久, 幸子
× 近久, 幸子× 勢井, 宏義
WEKO
1549
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| 抄録 | ||||||||||||
| 内容記述 | One of the functions of sleep is to maintain energy balance in the brain. There are a variety of hypotheses related to how metabolic pathways interact with sleep/wake regulation. A major finding that demonstrates an interaction between sleep and metabolic homeostasis is the involvement of adenosine in sleep homeostasis. An accumulation of adenosine is supplied from ATP, which can act as an energy currency in the cell. Extracellularly, ATP can act as an activity-dependent signaling molecule, especially in regard to communication between neurons and glia, including astrocytes. Furthermore, the intracellular AMP/ATP ratio controls the activity of AMP-activated protein kinase, which is a potent energy regulator and is recently reported to play a role in the regulation of sleep homeostasis. Brain ATP may support multiple functions in the regulation of the sleep/wake cycle and sleep homeostasis. | |||||||||||
| キーワード | ||||||||||||
| 主題 | sleep | |||||||||||
| キーワード | ||||||||||||
| 主題 | ATP | |||||||||||
| キーワード | ||||||||||||
| 主題 | adenosine | |||||||||||
| キーワード | ||||||||||||
| 主題 | astrocyte | |||||||||||
| キーワード | ||||||||||||
| 主題 | AMPK | |||||||||||
| 書誌情報 |
en : Frontiers in Neurology 巻 2, p. 87, 発行日 2011-12-27 |
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| 収録物ID | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 16642295 | |||||||||||
| 出版者 | ||||||||||||
| 出版者 | Frontiers Media SA | |||||||||||
| 権利情報 | ||||||||||||
| 権利情報 | © 2011 Chikahisa and Séi. This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited. | |||||||||||
| EID | ||||||||||||
| 識別子 | 252074 | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
