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Surgical treatment of locally advanced papillary thyroid carcinoma after response to lenvatinib : A case report
https://tokushima-u.repo.nii.ac.jp/records/2008101
https://tokushima-u.repo.nii.ac.jp/records/20081016bd3f066-5a52-481c-b453-ef5cc1dc7f70
| 名前 / ファイル | ライセンス | アクション |
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ijscr_41_89.pdf (1020 KB)
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| Item type | 文献 / Documents(1) | |||||||||||||||||||||||
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| 公開日 | 2021-02-18 | |||||||||||||||||||||||
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| アクセス権 | open access | |||||||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||||||
| 出版社版DOI | ||||||||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||||||||
| 関連識別子 | https://doi.org/10.1016/j.ijscr.2017.10.010 | |||||||||||||||||||||||
| 言語 | ja | |||||||||||||||||||||||
| 関連名称 | 10.1016/j.ijscr.2017.10.010 | |||||||||||||||||||||||
| 出版タイプ | ||||||||||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||||||
| タイトル | ||||||||||||||||||||||||
| タイトル | Surgical treatment of locally advanced papillary thyroid carcinoma after response to lenvatinib : A case report | |||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||
| 著者 |
坪井, 光弘
× 坪井, 光弘× 滝沢, 宏光
WEKO
1214
× (青山)三崎, 万理子
WEKO
1012
× 丹黒, 章
WEKO
176
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| 内容記述タイプ | Abstract | |||||||||||||||||||||||
| 内容記述 | INTRODUCTION: Differentiated thyroid carcinomas (DTC) have good prognoses after complete resection. Nevertheless, when DTC is associated with an aerodigestive invasion, curative surgery is difficult to perform. However, there is no established neoadjuvant therapy for advanced DTC. PRESENTATION OF CASE: A 73-year-old man with thyroid papillary carcinoma was referred to our hospital. A computed tomography examination revealed a tumor in the upper right lobe of the thyroid, and multiple bilateral enlarged lymph nodes in the neck, involving the surrounding structures. The enlarged lymph node at the right upper neck was suspected to have invaded the right internal jugular vein, and the left paratracheal lymph node was suspected to have invaded the cervical esophagus and trachea. The tumor was considered resectable; however, surgery would have been highly invasive. Therefore, we initiated neoadjuvant therapy with lenvatinib. After administration of lenvatinib, the tumor decreased in size by 84.3% and the cervical lymph nodes by 56.0%. The patient underwent a total thyroidectomy, modified neck dissection, a resection of the muscular layer of the esophagus, and a tracheal sleeve resection and reconstruction. DISCUSSION: The SELECT trial demonstrated that lenvatinib had high response rate with short response time, in patients with radioiodine-refractory DTC. The results suggested that lenvatinib could be effective as neoadjuvant therapy. CONCLUSION: For an advanced DTC that requires removal through invasive surgery, preoperative lenvatinib treatment might be one of the options for a less invasive surgery. |
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| 言語 | en | |||||||||||||||||||||||
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| 言語 | en | |||||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||||
| 主題 | Case report | |||||||||||||||||||||||
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| 言語 | en | |||||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||||
| 主題 | Papillary thyroid carcinoma | |||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||||
| 主題 | Lenvatinib | |||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||||
| 主題 | Neoadjuvant chemotherapy | |||||||||||||||||||||||
| 書誌情報 |
en : International Journal of Surgery Case Reports 巻 41, p. 89-92, 発行日 2017-10-14 |
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| 収録物識別子タイプ | ISSN | |||||||||||||||||||||||
| 収録物識別子 | 22102612 | |||||||||||||||||||||||
| 出版者 | ||||||||||||||||||||||||
| 出版者 | IJS Publishing Group | |||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||
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| 出版者 | Elsevier | |||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||
| 権利情報 | ||||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||
| 権利情報 | This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). | |||||||||||||||||||||||
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| 識別子 | 335759 | |||||||||||||||||||||||
| 識別子タイプ | URI | |||||||||||||||||||||||
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| 言語 | eng | |||||||||||||||||||||||
