| Item type |
文献 / Documents(1) |
| 公開日 |
2021-01-19 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.3389/fneur.2019.00046 |
|
|
言語 |
ja |
|
|
関連名称 |
10.3389/fneur.2019.00046 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Three-Dimensional Magnetic Resonance Imaging Reveals the Relationship Between the Control of Vertigo and Decreases in Endolymphatic Hydrops After Endolymphatic Sac Drainage With Steroids for Meniere’s Disease |
|
言語 |
en |
| タイトル別表記 |
|
|
その他のタイトル |
Endolymphatic Hydrops After Sac Surgery |
|
言語 |
en |
| 著者 |
イトウ, タエコ
イヌイ, ヒロシ
ミヤサカ, トシテル
シオザキ, トモユキ
マツヤマ, ショウヘイ
ヤマナカ, トシアキ
キチカワ, キミヒコ
武田, 憲昭
キタハラ, タダシ
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Meniere’s disease is a common disease, that presents with recurrent vertigo and cochlear symptoms. The pathology of Meniere’s disease was first reported to involve endolymphatic hydrops in 1938. The endolymphatic sac is thought to have a role to keep the hydrostatic pressure and endolymph homeostasis for the inner ear. As a surgery for intractable Meniere’s disease, endolymphatic sac drainage with intraendolymphatic sac application of large doses of steroids is performed to control the endolymphatic hydrops and preserve or improve inner ear function. In the present study, to observe the effect of this surgery, we calculated the endolymphatic space size using 3-Teslamagnetic resonance imaging (MRI) 4 h after intravenous injection of gadolinium enhancement at two time points: just before surgery and 2 years after. To reveal the condition of the endolymphatic space, we constructed three-dimensional MR images semi-automatically and fused the three-dimensional images of the total fluid space of inner ear and the endolymphatic space. After fusing the images, we calculated the volume of the total fluid space and endolymphatic space. Two years after surgery, 16 of 20 patients (80.0%) showed relief from vertigo/dizziness and reductions in the ratio of the volume of the endolymphatic size to the total fluid space of inner ear. Endolymphatic sac drainage with intraendolymphatic sac application of large doses of steroids could control vertigo/dizziness and decrease the endolymphatic hydrops. These results indicate that endolymphatic sac drainage is a good treatment option for patients with intractable Meniere’s disease. In addition, volumetric measurement of inner ear volume could be useful for confirming the effect of treatments on Meniere’s disease. |
|
言語 |
en |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
endolymphatic hydrops |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Meniere’s disease |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
surgery |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
MRI |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
endolymphatic sac |
| 書誌情報 |
en : Frontiers in Neurology
巻 10,
p. 46,
発行日 2019-02-04
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
16642295 |
| 出版者 |
|
|
出版者 |
Frontiers Media S.A. |
|
言語 |
en |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| EID |
|
|
識別子 |
365512 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
fneur_10_46.pdf (2.07 MB)
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