| Item type |
文献 / Documents(1) |
| 公開日 |
2021-03-19 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.3390/molecules24091689 |
|
|
言語 |
ja |
|
|
関連名称 |
10.3390/molecules24091689 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Distribution of Polysulfide in Human Biological Fluids and Their Association with Amylase and Sperm Activities |
|
言語 |
en |
| 著者 |
イケダ, マユミ
異島, 優
Chuang, Victor T. G.
サカイ, マキ
オサフネ, ヒロキ
安藤, 英紀
清水, 太郎
奥平, 桂一郎
ワタナベ, ヒロシ
マルヤマ, トオル
オタギリ, マサキ
アカイケ, タカアキ
石田, 竜弘
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Intracellular polysulfide could regulate the redox balance via its anti-oxidant activity. However, the existence of polysulfide in biological fluids still remains unknown. Recently, we developed a quantitative analytical method for polysulfide and discovered that polysulfide exists in plasma and responds to oxidative stress. In this study, we confirmed the presence of polysulfide in other biological fluids, such as semen and nasal discharge. The levels of polysulfide in these biological fluids from healthy volunteers (n = 9) with identical characteristics were compared. Additionally, the circadian rhythm of plasma polysulfide was also investigated. The polysulfide levels detected from nasal discharge and seminal fluid were approximately 400 and 600 μM, respectively. No correlation could be found between plasma polysulfide and the polysulfide levels of tear, saliva, and nasal discharge. On the other hand, seminal polysulfide was positively correlated with plasma polysulfide, and almost all polysulfide contained in semen was found in seminal fluid. Intriguingly, saliva and seminal polysulfide strongly correlated with salivary amylase and sperm activities, respectively. These results provide a foundation for scientific breakthroughs in various research areas like infertility and the digestive system process. |
|
言語 |
en |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
polysulfide |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
biological fluids |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
circadian rhythm |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
aging |
| 書誌情報 |
en : Molecules
巻 24,
号 9,
p. 1689,
発行日 2019-04-30
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
14203049 |
| 出版者 |
|
|
出版者 |
MDPI |
|
言語 |
en |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| EID |
|
|
識別子 |
351999 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
molecules_24_9_1689.pdf (2.19 MB)
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