| Item type |
文献 / Documents(1) |
| 公開日 |
2021-04-16 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
関連識別子 |
https://doi.org/10.1016/j.clnesp.2021.01.023 |
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|
関連名称 |
10.1016/j.clnesp.2021.01.023 |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| タイトル |
|
|
タイトル |
Malnutrition by European Society for Clinical Nutrition and Metabolism criteria predicts prognosis in patients with gastrointestinal and hepatobiliary–pancreatic cancer |
| 著者 |
アオタニ, ノゾミ
(安井)山田, 苑子
カギヤ, ナツミ
タキモト, マミ
オオイワ, ユウ
マツバラ, アツミ
マツウラ, サヤカ
タニムラ, マユ
(谷)鈴木, 佳子
柏原, 秀也
齋藤, 裕
西, 正暁
島田, 光生
濵田, 康弘
|
| 抄録 |
|
|
内容記述 |
Background & Aims: The European Society for Clinical Nutrition and Metabolism (ESPEN) proposed the ESPEN diagnostic criteria (EDC) for malnutrition in 2015. There is no report on the association between the EDC and prognosis in patients with gastrointestinal (GI) and hepatobiliary–pancreatic (HBP) cancer. This study aimed to (1) determine the prevalence of EDC malnutrition, (2) investigate the validity of the EDC as a nutritional and prognostic indicator, and (3) examine which components of the EDC are most related to long-term prognosis in patients with GI and HBP cancers.
Methods: A total of 634 patients with primary GI and HBP cancers who underwent their first resection surgery between July 2014 and March 2018 were retrospectively recruited. According to the EDC, patients were divided into malnourished and non-malnourished groups. Clinical parameters and survival between these two groups were compared. The prognostic effects of the EDC and the EDC components were analyzed using Cox proportional hazard models.
Results: The prevalence of EDC malnutrition was 22%. Anthropometric data and biochemical data were associated with EDC malnutrition. The 5-year survival rate was lower in the malnourished group (72%) than in the non-malnourished group (73%; P = 0.007). The multivariate analysis demonstrated that the malnourished group was an independent risk factor for mortality (hazard ratio = 1.70 in the malnourished group; 95% confidence interval 1.08–2.63; P = 0.024). Among EDC components, body mass index (BMI) of <18.5 kg/m2 was an independent poor prognostic factor.
Conclusions: EDC malnutrition is associated with poor postoperative long-term prognosis. Among the EDC components, BMI of <18.5 kg/m2 is most associated with prognosis in patients with preoperative GI and HBP cancers. |
| キーワード |
|
|
主題 |
ESPEN diagnostic criteria |
| キーワード |
|
|
主題 |
Malnutrition |
| キーワード |
|
|
主題 |
Body mass index |
| キーワード |
|
|
主題 |
Fat-free mass index |
| キーワード |
|
|
主題 |
Gastrointestinal cancer |
| キーワード |
|
|
主題 |
Prognosis |
| 書誌情報 |
en : Clinical Nutrition ESPEN
巻 42,
p. 265-271,
発行日 2021-02-11
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| 収録物ID |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
24054577 |
| 出版者 |
|
|
出版者 |
Elsevier |
| 出版者 |
|
|
出版者 |
European Society for Clinical Nutrition and Metabolism |
| 権利情報 |
|
|
権利情報 |
© 2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| EID |
|
|
識別子 |
374850 |
| 言語 |
|
|
言語 |
eng |
clnesp_42_265.pdf (508 KB)
