| Item type |
文献 / Documents(1) |
| 公開日 |
2021-08-19 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.1063/5.0054688 |
|
|
言語 |
ja |
|
|
関連名称 |
10.1063/5.0054688 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Charge-independent protein adsorption characteristics of epitaxial graphene field-effect transistor on SiC substrate |
|
言語 |
en |
| 著者 |
ナカイ, ヒロキ
アキヤマ, ダイウ
タニグチ, ヨシアキ
キシノブ, イオリ
ワリイシ, ヒロミチ
大野, 恭秀
永瀬, 雅夫
イケダ, タクヤ
田端, 厚之
長宗, 秀明
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Charge-independent biomolecule detection using field-effect transistors (FETs) with single-crystal and large-area epitaxial graphene films fabricated on SiC substrates is demonstrated. To obtain clean graphene channel surfaces, FETs were fabricated using stencil mask lithography, which is a resist-free fabrication process. Proteins with various isoelectric points (pI: 5.6–9.9) were used as targets. Transfer characteristics [drain current (𝐼D) vs solution-gate voltage (𝑉G) characteristics] were measured by changing the pH of the buffer solution. The 𝐼D–𝑉G characteristics exhibited a clear negative gate voltage shift for both positively and negatively charged proteins, indicating that the epitaxial graphene FETs could not detect the charge type of the protein and electrons were doped by the adsorption of both positively and negatively charged proteins. These results cannot be explained by conventional electrostatic effects. Therefore, it can be concluded that the detection of biomolecules by the epitaxial graphene FETs occurred through charge transfer from the proteins. Moreover, the dissociation constants between the proteins and epitaxial graphene films were as small as 100 pM, indicating the high sensitivity of the graphene FETs. |
|
言語 |
en |
| 書誌情報 |
en : Journal of Applied Physics
巻 130,
号 7,
p. 074502,
発行日 2021-08-16
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
00218979 |
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
10897550 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00693547 |
| 出版者 |
|
|
出版者 |
AIP Publishing |
|
言語 |
en |
| 備考 |
|
|
言語 |
ja |
|
値 |
This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Journal of Applied Physics 130, 074502 (2021) and may be found at https://doi.org/10.1063/5.0054688. |
| EID |
|
|
識別子 |
379456 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
jap_130_7_074502.pdf (1.99 MB)
