Differences in Several Factors in the Development of Erosive Esophagitis Among Patients at Various Stages of Metabolic Syndrome : A Cross-Sectional Study

曽我部, 正弘; ソガベ, マサヒロ; Sogabe, Masahiro; 岡久, 稔也; オカヒサ, トシヤ; Okahisa, Toshiya; クリハラ, タケシ; クリハラ, タケシ; Kurihara, Takeshi; 香川, 美和子; カガワ, ミワコ; Kagawa, Miwako; 影本, 開三; カゲモト, カイゾウ; Kagemoto, Kaizo; 喜田, 慶史; キダ, ヨシフミ; Kida, Yoshifumi; 友成, 哲; トモナリ, テツ; Tomonari, Tetsu; 谷口, 達哉; タニグチ, タツヤ; Taniguchi, Tatsuya; 岡本, 耕一; オカモト, コウイチ; Okamoto, Koichi; 宮本, 弘志; ミヤモト, ヒロシ; Miyamoto, Hiroshi; 佐藤, 康史; サトウ, ヤスシ; Sato, Yasushi; ナカソノ, マサヒコ; ナカソノ, マサヒコ; Nakasono, Masahiko; 高山, 哲治; タカヤマ, テツジ; Takayama, Tetsuji

doi:https://doi.org/10.2147/DMSO.S298326

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Differences in Several Factors in the Development of Erosive Esophagitis Among Patients at Various Stages of Metabolic Syndrome : A Cross-Sectional Study

https://tokushima-u.repo.nii.ac.jp/records/2009213

名前 / ファイル	ライセンス	アクション
dmso_14_1589.pdf (574 KB)

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文献 / Documents(1)

公開日

2021-09-28

アクセス権

open access

資源タイプ

資源タイプ識別子

http://purl.org/coar/resource_type/c_6501

資源タイプ

journal article

出版社版DOI

識別子タイプ

DOI

関連名称

10.2147/DMSO.S298326

出版タイプ

VoR

出版タイプResource

http://purl.org/coar/version/c_970fb48d4fbd8a85

タイトル

Differences in Several Factors in the Development of Erosive Esophagitis Among Patients at Various Stages of Metabolic Syndrome : A Cross-Sectional Study

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著者

曽我部, 正弘

WEKO 677
徳島大学教育研究者総覧 274188/profile-ja.html
e-Rad_Researcher 60732790

ja	曽我部, 正弘 ISNI
ja-Kana	ソガベ, マサヒロ
en	Sogabe, Masahiro

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岡久, 稔也

WEKO 1555
徳島大学教育研究者総覧 60090/profile-ja.html
e-Rad_Researcher 60304515

ja	岡久, 稔也 ISNI
ja-Kana	オカヒサ, トシヤ
en	Okahisa, Toshiya

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クリハラ, タケシ

ja	クリハラ, タケシ
ja-Kana	クリハラ, タケシ
en	Kurihara, Takeshi

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香川, 美和子

ja	香川, 美和子
ja-Kana	カガワ, ミワコ
en	Kagawa, Miwako

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影本, 開三

WEKO 1300
徳島大学教育研究者総覧 395217/profile-ja.html
e-Rad_Researcher 60933356

ja	影本, 開三
ja-Kana	カゲモト, カイゾウ
en	Kagemoto, Kaizo

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喜田, 慶史

WEKO 1172
徳島大学教育研究者総覧 364663/profile-ja.html
e-Rad_Researcher 80747650

ja	喜田, 慶史 ISNI
ja-Kana	キダ, ヨシフミ
en	Kida, Yoshifumi

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友成, 哲

WEKO 709
徳島大学教育研究者総覧 277740/profile-ja.html
e-Rad_Researcher 20556807

ja	友成, 哲 ISNI
ja-Kana	トモナリ, テツ
en	Tomonari, Tetsu

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谷口, 達哉

WEKO 633
e-Rad_Researcher 70518232

ja	谷口, 達哉 ISNI
ja-Kana	タニグチ, タツヤ
en	Taniguchi, Tatsuya

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岡本, 耕一

WEKO 349
徳島大学教育研究者総覧 179139/profile-ja.html
e-Rad_Researcher 60531374

ja	岡本, 耕一 ISNI
ja-Kana	オカモト, コウイチ
en	Okamoto, Koichi

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宮本, 弘志

WEKO 175
徳島大学教育研究者総覧 111468/profile-ja.html
e-Rad_Researcher 90398024

ja	宮本, 弘志 ISNI
ja-Kana	ミヤモト, ヒロシ
en	Miyamoto, Hiroshi

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佐藤, 康史

WEKO 852
徳島大学教育研究者総覧 321662/profile-ja.html

ja	佐藤, 康史 ISNI
ja-Kana	サトウ, ヤスシ
en	Sato, Yasushi

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ナカソノ, マサヒコ

ja	ナカソノ, マサヒコ
ja-Kana	ナカソノ, マサヒコ
en	Nakasono, Masahiko

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高山, 哲治

WEKO 287
徳島大学教育研究者総覧 169695/profile-ja.html
e-Rad_Researcher 10284994

ja	高山, 哲治 ISNI
ja-Kana	タカヤマ, テツジ
en	Takayama, Tetsuji

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抄録

内容記述タイプ

Abstract

内容記述

Background: Erosive esophagitis (EE) is strongly associated with metabolic syndrome (MS), but is not always recognized in individuals with MS and the prevalence of EE in individuals with non-MS is not low.
Aim: To examine the differences in clinical factors associated with EE at various stages of MS, as well as the differences in metabolites between subjects with MS, with and without EE.
Methods: A total of 7,097 persons who underwent health checkups including esophagogastroduodenoscopy were analyzed. We examined the differences in clinical factors for EE among subjects with non-MS, pre-MS, and MS and compared metabolites between 34 subjects with MS, with and without EE.
Results: EE prevalence was significantly higher in the MS and pre-MS groups than in the non-MS group (p < 0.001). EE severity was higher in the MS group than in the pre-MS and non-MS groups (p < 0.001). In the non-MS group, there were significant differences between subjects with and without EE with respect to Helicobacter pylori (H. pylori) and smoking. In the pre-MS and MS groups, there were significant differences in H. pylori, hiatal hernia, and drinking in those with and without EE. The levels of glutamine, hypoxanthine, and lactic acid metabolites were significantly different between subjects with MS, with and without EE (all p < 0.05).
Conclusion: Although H. pylori and lifestyle factors such as smoking and drinking are important for EE, differences in these factors should be considered at various stages of MS. Additionally, several metabolites may be involved in the development of EE in MS.

言語

キーワード

言語

主題Scheme

Other

主題

metabolic syndrome

キーワード

言語

主題Scheme

Other

主題

erosive esophagitis

キーワード

言語

主題Scheme

Other

主題

metabolite analysis

書誌情報

en : Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy

巻 14, p. 1589-1600, 発行日 2021-04-12

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ISSN

収録物識別子

11787007

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Dove Medical Press

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権利情報

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms. php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

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375132

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Differences in Several Factors in the Development of Erosive Esophagitis Among Patients at Various Stages of Metabolic Syndrome : A Cross-Sectional Study

× 曽我部, 正弘

× 岡久, 稔也

× クリハラ, タケシ

× 香川, 美和子

× 影本, 開三

× 喜田, 慶史

× 友成, 哲

× 谷口, 達哉

× 岡本, 耕一

× 宮本, 弘志

× 佐藤, 康史

× ナカソノ, マサヒコ

× 高山, 哲治

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