| Item type |
文献 / Documents(1) |
| 公開日 |
2021-09-21 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.2147/JPR.S188362 |
|
|
言語 |
ja |
|
|
関連名称 |
10.2147/JPR.S188362 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Pharmacotherapeutic outcomes in atypical odontalgia : determinants of pain relief |
|
言語 |
en |
| 著者 |
Tu, Trang TH
ミウラ, アンナ
シノハラ, ユキコ
ミクヅキ, ルウ
カワサキ, カオル
スガワラ, シオリ
スガ, タカユキ
渡邊, 毅
アオタ, ユウマ
ウメザキ, ヨウジロウ
タケノシタ, ミホ
トヨフク, アキラ
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Objectives: There has been considerable research which has focused on clarifying the origin of pain in patients with atypical odontalgia (AO), also known as “idiopathic toothache”, and on identifying effective treatment, but there has been limited success so far. In this study, we assessed the outcomes of treatment and attempted to identify factors that could account for pain remission in patients with AO.
Patients and methods: Data for 165 patients diagnosed with AO from June 2015 to August 2017 were retrospectively reviewed. The patients’ sex, age, duration of pain, and psychiatric history were collected, along with information on pain intensity, depressive status, and catastrophizing scores. Responses at 4 and 16 weeks from the start of treatment were observed. The associations between potentially associated factors and outcome were investigated using Bayesian model averaging.
Results: A 30% reduction in pain was reported by 38 patients (46.3%) at 4 weeks and by 54 patients (65.9%) at 16 weeks. The pain intensity decreased as the depression and catastrophizing score improved; all of the changes were statistically significant (P<0.001). Four elements, that is, patient sex, depression score at baseline, pain score at 4 weeks, and change in the catastrophizing score, explained 52.5% of the variation in final outcome between individual patients.
Conclusion: Our findings confirm the efficacy of tricyclic antidepressants (TCAs) as a treatment for AO and indicate that other medications, especially aripiprazole used in combination with a TCA, may be useful. A considerable number of patients, especially women, those with lower levels of depression at baseline, and those who responded to 4 weeks of treatment, achieved pain relief. |
|
言語 |
en |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
atypical odontalgia |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
orofacial chronic pain |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
depression |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
pain catastrophizing |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
tricyclic antidepressant |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
atypical antipsychotic |
| 書誌情報 |
en : Journal of Pain Research
巻 12,
p. 831-839,
発行日 2019-02-27
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
11787090 |
| 出版者 |
|
|
出版者 |
Dove Medical Press |
|
言語 |
en |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms. php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
| EID |
|
|
識別子 |
382023 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
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