Item type |
文献 / Documents(1) |
公開日 |
2022-02-21 |
アクセス権 |
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アクセス権 |
open access |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
出版社版DOI |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1155/2021/1583154 |
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言語 |
ja |
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関連名称 |
10.1155/2021/1583154 |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
タイトル |
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タイトル |
Effect of Continuous Feeding of Ayu-Narezushi on Lipid Metabolism in a Mouse Model of Metabolic Syndrome |
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言語 |
en |
著者 |
ニシダ, タケシ
常山, 幸一
タゴ, ヤスヒコ
ノムラ, コウジ
フジモト, マコト
ナカジマ, タカヒコ
ノグチ, アキラ
ミナミサカ, タカシ
ハッタ, ヒデキ
イムラ, ジョウジ
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抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Ayu-narezushi, a traditional Japanese fermented food, comprises abundant levels of lactic acid bacteria (LAB) and free amino acids. This study aimed to examine the potential beneficial effects of ayu-narezushi and investigated whether ayu-narezushi led to improvements in the Tsumura Suzuki obese diabetes (TSOD) mice model of spontaneous metabolic syndrome because useful LAB are known as probiotics that regulate intestinal function. In the present study, the increased body weight of the TSOD mice was attenuated in those fed the ayu-narezushi-comprised chow (ayu-narezushi group) compared with those fed the normal rodent chow (control group). Serum triglyceride and cholesterol levels were significantly lower in the Ayu-narezushi group than in the control group at 24 weeks of age. Furthermore, hepatic mRNA levels of carnitine-palmitoyl transferase 1 and acyl-CoA oxidase, which related to fatty acid oxidation, were significantly increased in the ayu-narezushi group than in the control group at 24 weeks of age. In conclusion, these results suggested that continuous feeding with ayu-narezushi improved obesity and dyslipidemia in the TSOD mice and that the activation of fatty acid oxidation in the liver might contribute to these improvements. |
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言語 |
en |
書誌情報 |
en : The Scientific World Journal
巻 2021,
p. 1583154,
発行日 2021-09-07
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収録物ID |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
23566140 |
収録物ID |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1537744X |
出版者 |
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出版者 |
Hindawi |
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言語 |
en |
権利情報 |
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言語 |
en |
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権利情報 |
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
EID |
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識別子 |
384224 |
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識別子タイプ |
URI |
言語 |
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言語 |
eng |