| Item type |
文献 / Documents(1) |
| 公開日 |
2022-04-08 |
| アクセス権 |
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|
アクセス権 |
open access |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
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|
関連識別子 |
https://doi.org/10.3390/nu14050943 |
|
|
関連名称 |
10.3390/nu14050943 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Development and Validation of Cutoff Value for Reduced Muscle Mass for GLIM Criteria in Patients with Gastrointestinal and Hepatobiliary–Pancreatic Cancers |
| 著者 |
タキモト, マミ
(安井)山田, 苑子
ナス, ナナミ
カギヤ, ナツミ
アオタニ, ノゾミ
黒川, 有美子
(谷)鈴木, 佳子
柏原, 秀也
齋藤, 裕
西, 正暁
島田, 光生
濵田, 康弘
|
| 抄録 |
|
|
内容記述 |
The Global Leadership Initiative on Malnutrition (GLIM) criteria recommends using race- and sex-adjusted cutoff values for reduced muscle mass (RMM), but the only cutoff values available for Asians are the skeletal muscle mass index (SMI) established by the Asian Working Group for Sarcopenia (AWGS). This retrospective study aimed to develop and validate cutoff values for the fat-free mass index (FFMI) and arm circumference (AC) of Asians, and to investigate the association between GLIM malnutrition and prognosis. A total of 660 patients with primary gastrointestinal (GI) and hepatobiliary–pancreatic (HBP) cancers who underwent their first resection surgery were recruited and randomly divided into development and validation groups. The FFMI and AC cutoff values were calculated by receiver operating characteristic curve analysis for the AWGS SMI as the gold standard. The cutoff values for each RMM were used to diagnose malnutrition on the basis of GLIM criteria, and the survival rates were compared. The optimal FFMI cutoff values for RMM were 17 kg/m2 for men and 15 kg/m2 for women, and for AC were 27 cm for men and 25 cm for women. In the validation group, the accuracy of the FFMI and AC cutoff values to discriminate RMM were 85.2% and 68.8%, respectively. Using any of the three measures of RMM, overall survival rates were significantly lower in the GLIM malnutrition group. In conclusion, the cutoff values for the FFMI and AC in this study could discriminate RMM, and GLIM malnutrition using these cutoff values was associated with decreased survival. |
| キーワード |
|
|
主題 |
Global Leadership Initiative on Malnutrition |
| キーワード |
|
|
主題 |
reduced muscle mass |
| キーワード |
|
|
主題 |
cutoff value |
| キーワード |
|
|
主題 |
fat-free mass index |
| キーワード |
|
|
主題 |
arm circumference |
| キーワード |
|
|
主題 |
gastrointestinal cancer |
| 書誌情報 |
en : Nutrients
巻 14,
号 5,
p. 943,
発行日 2022-02-23
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| 収録物ID |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
20726643 |
| 出版者 |
|
|
出版者 |
MDPI |
| 権利情報 |
|
|
権利情報 |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| EID |
|
|
識別子 |
384953 |
| 言語 |
|
|
言語 |
eng |
nu_14_5_943.pdf (827 KB)
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