Item type |
文献 / Documents(1) |
公開日 |
2022-08-30 |
アクセス権 |
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アクセス権 |
open access |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
出版社版DOI |
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関連識別子 |
https://doi.org/10.1111/1759-7714.14243 |
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関連名称 |
10.1111/1759-7714.14243 |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
タイトル |
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タイトル |
A case of pulmonary pleomorphic carcinoma with preexisting interstitial pneumonia successfully treated with pembrolizumab |
著者 |
サコ, マサヒロ
軒原, 浩
コンドウ, ケンスケ
三橋, 惇志
尾崎, 領彦
矢葺, 洋平
阿部, あかね
米田, 浩人
荻野, 広和
大塚, 憲司
上原, 久典
西岡, 安彦
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抄録 |
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内容記述 |
Pulmonary pleomorphic carcinoma is often refractory to chemotherapy and follows an aggressive clinical course. Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of advanced lung cancer, and a few cases with pleomorphic carcinoma have been reported to show tumor shrinkage after therapy with ICIs. When treating patients with ICIs, patient selection is essential, and monitoring and management of immune-related adverse events, including pneumonitis, are needed. We herein report a case of pulmonary pleomorphic carcinoma with preexisting interstitial pneumonia treated with pembrolizumab, antiprogrammed cell death 1 antibody. Our report highlights important considerations necessary when treating advanced pleomorphic carcinoma patients complicated with interstitial pneumonia. We also review the literature regarding the use of ICIs in such patients. |
キーワード |
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主題 |
interstitial pneumonia |
キーワード |
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主題 |
pembrolizumab |
キーワード |
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主題 |
pulmonary pleomorphic carcinoma |
書誌情報 |
en : Thoracic Cancer
巻 13,
号 1,
p. 129-132,
発行日 2021-12-03
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収録物ID |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
17597714 |
出版者 |
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出版者 |
China Lung Oncology Group |
出版者 |
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出版者 |
John Wiley & Sons Australia |
権利情報 |
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権利情報 |
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
EID |
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識別子 |
387238 |
言語 |
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言語 |
eng |