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Identifying vertebral fractures in the Japanese population using the trabecular bone score : a cross-sectional study
https://tokushima-u.repo.nii.ac.jp/records/2010793
https://tokushima-u.repo.nii.ac.jp/records/2010793c5180661-7c3a-4776-bf88-99e2780ba6e1
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bmcmd_23_976.pdf (1.5 MB)
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| 公開日 | 2023-03-15 | |||||||||||||||||||||||||||||||||||
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| アクセス権 | open access | |||||||||||||||||||||||||||||||||||
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| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||||||||||||||||||
| 出版社版DOI | ||||||||||||||||||||||||||||||||||||
| 関連識別子 | https://doi.org/10.1186/s12891-022-05839-z | |||||||||||||||||||||||||||||||||||
| 関連名称 | 10.1186/s12891-022-05839-z | |||||||||||||||||||||||||||||||||||
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| 出版タイプ | VoR | |||||||||||||||||||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||||||||||||||||||
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| タイトル | Identifying vertebral fractures in the Japanese population using the trabecular bone score : a cross-sectional study | |||||||||||||||||||||||||||||||||||
| 著者 |
大道, 泰之
× 大道, 泰之
× ミマ, ノリアキ
× オカダ, リョウ
× 和田, 佳三× 森本, 雅俊
WEKO
1165
× 西良, 浩一
WEKO
1543
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| 内容記述 | Background: The trabecular bone score (TBS) is reported to be an independent predictor of fracture risk in patients with primary or secondary osteoporosis. However, there have been few reports on its use in the Japanese population. This study aimed to investigate the risk factors for vertebral fracture in the Japanese population and to evaluate the usefulness of TBS. Methods: This cross-sectional study involved 279 patients aged 60–90 years in whom bone mineral density (BMD) was measured by dual-energy X-ray absorptiometry (DXA). TBS was calculated based on the DXA scans. The presence or absence of vertebral fractures was assessed from T11 to L5. The patients were divided into those with vertebral fractures (VF group, n = 104) and those without vertebral fractures (non-VF group, n = 175). Results: Of the 104 patients in the VF group, 75 had 1 vertebral fracture and 29 had 2 or more fractures. The mean TBS was 1.28 in the VF group and 1.35 in the non-VF group (p < 0.001). The mean BMD values at the lumbar spine and femoral neck were lower in the VF group (p < 0.001). The areas under the receiver-operating characteristic curve for incidence of vertebral fractures were 0.700, 0.737, and 0.689 for TBS, lumbar spine BMD, and femoral neck BMD, respectively. Multiple logistic regression analysis identified lumbar spine BMD, TBS, and female sex as significant risk factors for vertebral fractures. The proportion of patients in the group with osteoporosis or osteopenia who had vertebral fractures was higher in those with a low TBS (≤ 1.23) than in those with a non-low TBS (> 1.23). Conclusion: TBS was a significant indicator of vertebral fractures in the Japanese population and might contribute to identifying patients with vertebral fractures, particularly those with osteopenia who need pharmacologic therapy. |
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| キーワード | ||||||||||||||||||||||||||||||||||||
| 主題 | Trabecular bone score | |||||||||||||||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||||||||||||||
| 主題 | Vertebral fracture | |||||||||||||||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||||||||||||||
| 主題 | Osteoporosis | |||||||||||||||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||||||||||||||
| 主題 | Japanese population | |||||||||||||||||||||||||||||||||||
| 書誌情報 |
en : BMC Musculoskeletal Disorders 巻 23, p. 976, 発行日 2022-11-11 |
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| 収録物識別子タイプ | ISSN | |||||||||||||||||||||||||||||||||||
| 収録物識別子 | 14712474 | |||||||||||||||||||||||||||||||||||
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| 収録物識別子タイプ | NCID | |||||||||||||||||||||||||||||||||||
| 収録物識別子 | AA12035278 | |||||||||||||||||||||||||||||||||||
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| 出版者 | Springer Nature | |||||||||||||||||||||||||||||||||||
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| 出版者 | BioMed Central | |||||||||||||||||||||||||||||||||||
| 権利情報 | ||||||||||||||||||||||||||||||||||||
| 権利情報 | This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. | |||||||||||||||||||||||||||||||||||
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| 識別子 | 393921 | |||||||||||||||||||||||||||||||||||
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| 言語 | eng | |||||||||||||||||||||||||||||||||||
