| Item type |
文献 / Documents(1) |
| 公開日 |
2023-03-22 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
関連識別子 |
https://doi.org/10.2169/internalmedicine.7118-21 |
|
|
関連名称 |
10.2169/internalmedicine.7118-21 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Glucocorticoid-dependent Tubulointerstitial Nephritis with IgM-positive Plasma Cells Presenting with Intracellular Crystalline Inclusions within the Rough Endoplasmic Reticulum |
| 著者 |
ミナト, マサノリ
村上, 太一
タカハシ, ナオキ
小野, 広幸
西村, 賢二
田蒔, 昌憲
長井, 幸二郎
安部, 秀斉
イワノ, マサユキ
ジョウ, ケンスケ
土井, 俊夫
|
| 抄録 |
|
|
内容記述 |
Tubulointerstitial nephritis (TIN) with IgM-positive plasma cells (IgMPC-TIN) is an autoimmune kidney disease characterized by IgM/CD138-double-positive plasma cell infiltration in the tubulointerstitium. A 50-year-old man developed IgMPC-TIN and presented with crystalline inclusions in the rough endoplasmic reticulum. Intracellular crystal formation is a rare finding in paraprotein-related kidney diseases, but this case showed no pathogenic monoclonal immunoglobulin. Prednisolone (PSL, 30 mg) improved the TIN, but PSL tapering resulted in the recurrence of TIN. Combination therapy with 15 mg PSL and 150 mg mizoribine ultimately stabilized TIN. This case offers original evidence concerning the pathophysiology and treatment strategy of IgMPC-TIN. |
| キーワード |
|
|
主題 |
tubulointerstitial nephritis with IgM-positive plasma cells |
| キーワード |
|
|
主題 |
intracellular crystalline inclusions in the rough endoplasmic reticulum |
| キーワード |
|
|
主題 |
glucocorticoid dependence |
| 書誌情報 |
en : Internal Medicine
巻 60,
号 19,
p. 3129-3136,
発行日 2021-10-01
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13497235 |
| 出版者 |
|
|
出版者 |
The Japanese Society of Internal Medicine |
| 権利情報 |
|
|
権利情報 |
The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
| EID |
|
|
識別子 |
381058 |
| 言語 |
|
|
言語 |
eng |
internalmedicine_60_19_3129.pdf (2.87 MB)
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