| Item type |
文献 / Documents(1) |
| 公開日 |
2023-09-11 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
関連識別子 |
https://doi.org/10.1002/jcsm.12775 |
|
|
関連名称 |
10.1002/jcsm.12775 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Home-based aerobic exercise and resistance training for severe chronic kidney disease : a randomized controlled trial |
| タイトル別表記 |
|
|
その他のタイトル |
Home-based aerobic exercise and resistance training |
| 著者 |
ウチヤマ, キヨタカ
アダチ, ケイカ
ムラオカ, カオリ
ナカヤマ, タカシン
オシダ, タクマ
ヤスダ, マリエ
ヒシカワ, アキヒト
ミナクチ, ヒトシ
ミヤシタ, カズトシ
トクヤマ, ヒロブミ
𦚰野, 修
イトウ, ヒロシ
|
| 抄録 |
|
|
内容記述 |
Background
The potential effects of aerobic and resistance training in patients with severe chronic kidney disease (CKD) are not fully elucidated. This study investigated the effects of a home-based exercise programme on physical functioning and health-related quality of life (HRQOL) in patients with Stage 4 CKD, equivalent to estimated glomerular filtration rate of 15–30 mL/min/1.73 m2.
Methods
Forty-six patients with Stage 4 CKD (median age, 73 years; 33 men) were randomly assigned to exercise (n = 23) and control (n = 23) groups. Exercise group patients performed aerobic exercise at 40–60% peak heart rate thrice weekly and resistance training at 70% of one-repetition maximum twice weekly at home for 6 months. Control patients received no specific intervention. Primary outcomes were distance in incremental shuttle walking test and HRQOL assessed using the Kidney Disease Quality of Life—Short Form questionnaire. Secondary outcomes included kidney function assessed with combined urea and creatinine clearance, urinary biomarkers, and anthropometric and biochemical parameters associated with CKD.
Results
Improvement in incremental shuttle walking test was significantly greater in the exercise group compared with controls (39.4 ± 54.6 vs. −21.3 ± 46.1; P < 0.001). Among Kidney Disease Quality of Life domains, significant mean differences were observed between the exercise group and the control group in work status, quality of social interaction, and kidney disease component summary outcomes (12.76 ± 5.76, P = 0.03; 5.97 ± 2.59, P = 0.03; and 4.81 ± 1.71, P = 0.007, respectively). There were greater reductions in natural log (ln)-transformed urinary excretion of liver-type fatty acid-binding protein, ln serum C-reactive protein, and acylcarnitine to free carnitine ratio in the exercise group compared with controls, with significant between-group differences of −0.579 ± 0.217 (P = 0.008), −1.13 ± 0.35 (P = 0.003), and −0. 058 ± 0.024 (P = 0.01), respectively.
Conclusions
Our 6 month home-based exercise programme improved aerobic capacity and HRQOL in patients with Stage 4 CKD, with possible beneficial effects on kidney function and CKD-related parameters. |
| キーワード |
|
|
主題 |
Home-based exercise |
| キーワード |
|
|
主題 |
Chronic kidney disease |
| キーワード |
|
|
主題 |
Randomized controlled trial |
| キーワード |
|
|
主題 |
Incremental shuttle walking test |
| キーワード |
|
|
主題 |
Quality of life |
| 書誌情報 |
en : Journal of Cachexia, Sarcopenia and Muscle
巻 12,
号 6,
p. 1789-1802,
発行日 2021-09-23
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
21906009 |
| 出版者 |
|
|
出版者 |
John Wiley & Sons |
| 出版者 |
|
|
出版者 |
The Society on Sarcopenia, Cachexia and Wasting Disorders |
| 権利情報 |
|
|
権利情報 |
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
| EID |
|
|
識別子 |
400906 |
| 言語 |
|
|
言語 |
eng |
jcsm_12_6_1789.pdf (562 KB)
.png)
