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Eosinophilic pleural effusion due to lung cancer has a better prognosis than non-eosinophilic malignant pleural effusion

https://tokushima-u.repo.nii.ac.jp/records/2011299
https://tokushima-u.repo.nii.ac.jp/records/2011299
eb6058fd-b5dd-49e5-9186-bef77bdf8b28
名前 / ファイル ライセンス アクション
cii_71_2_365.pdf cii_71_2_365.pdf (511 KB)
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アイテムタイプ 文献 / Documents(1)
公開日 2023-10-05
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
出版社版DOI
関連識別子 https://doi.org/10.1007/s00262-021-02994-5
関連名称 10.1007/s00262-021-02994-5
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
タイトル
タイトル Eosinophilic pleural effusion due to lung cancer has a better prognosis than non-eosinophilic malignant pleural effusion
著者 タケウチ, エイジ

× タケウチ, エイジ

ja タケウチ, エイジ

ja-Kana タケウチ, エイジ

en Takeuchi, Eiji

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オカノ, ヨシオ

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ja オカノ, ヨシオ

ja-Kana オカノ, ヨシオ

en Okano, Yoshio

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マチダ, ヒサノリ

× マチダ, ヒサノリ

ja マチダ, ヒサノリ

ja-Kana マチダ, ヒサノリ

en Machida, Hisanori

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安宅, 克博

× 安宅, 克博

ja 安宅, 克博

ja-Kana アタギ, カツヒロ

en Atagi, Katsuhiro

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コンドウ, ヨシヒロ

× コンドウ, ヨシヒロ

ja コンドウ, ヨシヒロ

ja-Kana コンドウ, ヨシヒロ

en Kondou, Yoshihiro

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カドタ, ナオキ

× カドタ, ナオキ

ja カドタ, ナオキ

ja-Kana カドタ, ナオキ

en Kadota, Naoki

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ハタケヤマ, ノブオ

× ハタケヤマ, ノブオ

ja ハタケヤマ, ノブオ

ja-Kana ハタケヤマ, ノブオ

en Hatakeyama, Nobuo

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ナルセ, ケイシ

× ナルセ, ケイシ

ja ナルセ, ケイシ

ja-Kana ナルセ, ケイシ

en Naruse, Keishi

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篠原, 勉

× 篠原, 勉

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徳島大学 教育研究者総覧 124424/profile-ja.html
e-Rad_Researcher 70284289

ja 篠原, 勉

ja-Kana シノハラ, ツトム

en Shinohara, Tsutomu

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抄録
内容記述 Objective
Tumor-related eosinophilia may have extended survival benefits for some cancer patients. However, there has been no report on the prognosis difference between eosinophilic pleural effusion (EPE) and non-EPE in lung cancer patients. Our study aimed to investigate the prognosis difference between EPE and non-EPE due to lung cancer.
Patients and methods
We retrospectively reviewed patients diagnosed with lung cancer who presented with malignant pleural effusion (MPE) between May 2007 and September 2020 at the National Hospital Organization Kochi Hospital. EPE is defined as pleural fluid with a nucleated cell count containing 10% or more eosinophils.
Results
A total of 152 patients were included: 89 were male (59%). The median age was 74.4 years (range 37–101), and all patients were pathologically shown to have MPE. Most patients (140; 92%) had an Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) of 0/1. Twenty patients had EPE. The median overall survival (OS) of all 152 lung cancer patients with MPE was 298 days. The median OS of the patients with EPE was 766 days, and the median OS of the patients with non-EPE was 252 days. Kaplan–Meier univariate analysis showed that lung cancer patients with EPE had a significantly better prognosis than patients with non-EPE (P < 0.05). Cox proportional regression analysis showed that EPE, ECOG PS, sex, and the neutrophil-to-lymphocyte ratio in the serum (sNLR) may be independent prognostic factors affecting survival in patients with MPE.
Conclusion
Lung cancer patients with EPE have a better prognosis than those with non-EPE.
キーワード
主題 Lung cancer
キーワード
主題 Malignant pleural effusion
キーワード
主題 Eosinophilic pleural effusion
キーワード
主題 Survival
キーワード
主題 Better prognosis
書誌情報 en : Cancer Immunology, Immunotherapy

巻 71, 号 2, p. 365-372, 発行日 2021-06-25
収録物ID
収録物識別子タイプ ISSN
収録物識別子 03407004
収録物ID
収録物識別子タイプ ISSN
収録物識別子 14320851
収録物ID
収録物識別子タイプ NCID
収録物識別子 AA00598499
出版者
出版者 Springer Nature
権利情報
権利情報 This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
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識別子 397306
言語
言語 eng
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